Evidence map›Paper›PMID 31357732›Full record

ArticleGenes2019

Association of Vitamin D Pathway Genetic Variation and Thyroid Cancer.

Isabel S Carvalho, Catarina I Gonçalves, Joana T Almeida, Teresa Azevedo, Teresa Martins, Fernando J Rodrigues, Manuel C Lemos

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Vitamin D-Related Genes and Thyroid Cancer-A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
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  11. High DHCR7 Expression Predicts Poor Prognosis for Cervical Cancer.Computational and mathematical methods in medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Isabel S CarvalhoCICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal.
Catarina I GonçalvesCICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal.
Joana T AlmeidaCICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal.
Teresa AzevedoServiço de Endocrinologia, Instituto Português de Oncologia de Coimbra, 3000-075 Coimbra, Portugal.
Teresa MartinsServiço de Endocrinologia, Instituto Português de Oncologia de Coimbra, 3000-075 Coimbra, Portugal.
Fernando J RodriguesServiço de Endocrinologia, Instituto Português de Oncologia de Coimbra, 3000-075 Coimbra, Portugal.
Manuel C LemosCICS-UBI, Health Sciences Research Centre, University of Beira Interior, 6200-506 Covilhã, Portugal. mclemos@fcsaude.ubi.pt.ORCID 0000-0001-9326-8900
University of Beira Interior · PTInstituto Português de Oncologia de Coimbra Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is mostly known for its role in bone and calcium metabolism. However, studies have suggested that it also has inhibitory effects on tumor development and progression. Genetic variants close to genes that encode crucial enzymes for the synthesis (

Indexed as

Polymorphism, Single NucleotideAdultCholestanetriol 26-MonooxygenaseCytochrome P450 Family 2FemaleHumansMaleMiddle AgedOxidoreductases Acting on CH-CH Group DonorsThyroid NeoplasmsVitamin DVitamin D3 24-Hydroxylase7-dehydrocholesterol reductaseCholestanetriol 26-MonooxygenaseCYP24A1 protein, humanCYP2R1 protein, humanCytochrome P450 Family 2Oxidoreductases Acting on CH-CH Group DonorsVitamin DVitamin D3 24-Hydroxylasegeneticspolymorphismsthyroid cancervitamin D

Identifiers

PMID31357732
PMCPMC6723605
OpenAlexW2965898410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.