Evidence map›Paper›PMID 31357711›Full record

ArticleGenes2019

Isabel Espinosa-Salinas, Rocio de la Iglesia, Gonzalo Colmenarejo, Susana Molina, Guillermo Reglero, J Alfredo Martinez, Viviana Loria-Kohen, Ana Ramirez de Molina

Registry-linked trialAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05772910 (Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05772910 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.

TypeinterventionalSponsorUniversity of CadizRan2024 to 2026Enrolled110ConditionsFrailty, Disability Physical, Old Age, AtrophyArmsEDUcation, EXERcise, EDU-EXER, CONtrol
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Sex-specific impact ofTherapeutic advances in endocrinology and metabolism · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabel Espinosa-SalinasNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.ORCID 0000-0002-9526-891X
Rocio de la IglesiaNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.ORCID 0000-0002-7472-3565
Gonzalo ColmenarejoBiostatistics and Bioinformatics Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.ORCID 0000-0002-8249-4547
Susana MolinaNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.
Guillermo RegleroNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.
J Alfredo MartinezNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain.ORCID 0000-0001-5218-6941
Viviana Loria-KohenNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain. viviana.loria@imdea.org.
Ana Ramirez de MolinaNutrition and Clinical Trials Unit, IMDEA Food CEI UAM + CSIC, 28049 Madrid, Spain. ana.ramirez@imdea.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise performance is influenced by genetics. However, there is a lack of knowledge about the role played by genetic variability in the frequency of physical exercise practice. The objective was to identify genetic variants that modulate the commitment of people to perform physical exercise and to detect those subjects with a lower frequency practice. A total of 451 subjects were genotyped for 64 genetic variants related to inflammation, circadian rhythms, vascular function as well as energy, lipid and carbohydrate metabolism. Physical exercise frequency question and a Minnesota Leisure Time Physical Activity Questionnaire (MLTPAQ) were used to qualitatively and quantitatively measure the average amount of physical exercise. Dietary intake and energy expenditure due to physical activity were also studied. Differences between genotypes were analyzed using linear and logistic models adjusted for Bonferroni. A significant association between

Indexed as

ExercisePolymorphism, Single NucleotideAdaptor Proteins, Signal TransducingAdolescentAdultFemaleHumansMaleMiddle AgedAdaptor Proteins, Signal TransducingGCKR protein, humanbehaviorexercisegenotypingglucokinase-regulatorobesity

Identifiers

PMID31357711
PMCPMC6722860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.