Evidence map›Paper›PMID 31357602›Full record

ArticleCancers2019

Anieta M Sieuwerts, Shusma C Doebar, Vanja de Weerd, Esther I Verhoef, Corine M Beauford, Marie C Agahozo, John W M Martens, Carolien H M van Deurzen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Clinical Implications of APOBEC3-Mediated Mutagenesis in Breast Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anieta M SieuwertsDepartment of Medical Oncology and Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1341-5400
Shusma C DoebarDepartment of Pathology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Vanja de WeerdDepartment of Medical Oncology and Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Esther I VerhoefDepartment of Pathology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Corine M BeaufordDepartment of Medical Oncology and Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Marie C AgahozoDepartment of Pathology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
John W M MartensDepartment of Medical Oncology and Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-3428-3366
Carolien H M van DeurzenDepartment of Pathology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands. c.h.m.vandeurzen@erasmusmc.nl.
Erasmus MC Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underlying mechanism of the progression of ductal carcinoma in situ (DCIS), a non-obligate precursor of invasive breast cancer (IBC), has yet to be elucidated. In IBC, Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B (APOBEC3B) is upregulated in a substantial proportion of cases and is associated with higher mutational load and poor prognosis. However, APOBEC3B expression has never been studied in DCIS. We performed mRNA expression analysis of

Indexed as

APOBEC3Bbreast cancerductal carcinoma in situgene expressioninfiltrating breast cancerPIK3CA

Identifiers

PMID31357602
PMCPMC6721358
OpenAlexW2965566026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.