Evidence map›Paper›PMID 31357573›Full record

ArticleInternational journal of environmental research and public health2019

Oxidative Stress Levels Induced by Mercury Exposure in Amazon Juvenile Populations in Brazil.

Leandro V B Carvalho, Sandra S Hacon, Claudia M Vega, Jucilene A Vieira, Ariane L Larentis, Rita C O C Mattos, Daniel Valente, Isabele C Costa-Amaral, Dennys S Mourão, Gabriela P Silva and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Oxidative Stress in Children and Adolescents: Insights Into Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Transcriptome Analysis Reveals HgClInternational journal of molecular sciences · 2021
    Article
  8. Associations of Metabolic Genes (International journal of environmental research and public health · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Leandro V B CarvalhoToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil. leandro.carvalho@ensp.fiocruz.br.ORCID 0000-0002-3090-7477
Sandra S HaconDepartment of Endemics Samuel Pessoa (DENSP), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Claudia M VegaDepartment of Endemics Samuel Pessoa (DENSP), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Jucilene A VieiraToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Ariane L LarentisToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Rita C O C MattosToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Daniel ValenteToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.ORCID 0000-0002-3750-5876
Isabele C Costa-AmaralToxicology Laboratory, Center for Studies of Worker's Health and Human Ecology (CESTEH), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Dennys S MourãoDepartment of Endemics Samuel Pessoa (DENSP), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.ORCID 0000-0002-5525-3123
Gabriela P SilvaDepartment of Endemics Samuel Pessoa (DENSP), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Beatriz F A OliveiraDepartment of Endemics Samuel Pessoa (DENSP), National School of Public Health Sergio Arouca (ENSP), Oswaldo Cruz Foundation (Fiocruz), Leopoldo Bulhões Street, 1480, Manguinhos, Rio de Janeiro-RJ, CEP 21041-210, Brazil.
Escola Nacional de Saúde Pública · BRAmazon (United States) · US

Funding

SUBTHRESHOLD MUSCLE AFFERENT INPUT TO DORSAL HORNF06TW002012 · FIC · UNIVERSITY OF CALIFORNIA DAVIS · PI KAUFMAN, MARC PETER · 1995 to 1995
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6 · The paper itself

Abstract

Oxidative stress can be induced by mercury (Hg) exposure, including through fish consumption (diet), leading to health risks. The objective of this study was to evaluate the association between oxidative stress biomarkers and dietary Hg exposure levels in riverine children and adoluiaescents at Madeira River (RO/Brazil). Population from three riverine local communities presenting different fish consumption frequencies was sampled. Hg was determined in blood (ICP-MS) and glutathione (GSH); glutathione S-transferases (GST) and malondialdehyde (MDA) were determined in serum (spectrophotometry). Statistical analyses were performed using parametric and non-parametric tests. Multiple linear regression models and generalized additives models were also used to estimate the relationships between oxidative stress biomarkers and blood Hg. The juvenile riverine population from Cuniã RESEX presented the highest levels of oxidative stress and Hg levels in blood (GST = 27.2 (4.93) U/L, MDA = 1.69 (0.27) µmol/L, Hg = 20.6 (18.0) µg/L). This population also presented the highest frequency of fish consumption. The positive relation between Hg and GST and MDA, adjusted for individual characteristics, suggests an oxidative effect. This study shows the importance of oxidative stress biomarkers in the evaluation of dietary Hg exposure since initial and reversible metabolic changes were observed, enriching health risk assessments.

Indexed as

Dietary ExposureRural PopulationAdolescentAdultAnimalsBiomarkersBrazilChildDietFemaleFishesHumansLinear ModelsMaleMercuryOxidative StressBiomarkersMercuryWater Pollutants, Chemicalbiomarkersjuvenile riverine communitiesmercury exposureoxidative stress

Identifiers

PMID31357573
PMCPMC6696106
OpenAlexW2966080492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.