ReviewInternational journal of molecular sciences2019
Arterial Stiffness Assessed by Cardio-Ankle Vascular Index.
Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Relationship of arterial tonometry and exercise in patients with chronic heart failure: a systematic review with meta-analysis and trial sequential analysis.BMC cardiovascular disorders · 2022Pooled it
- Exercise-Induced Oxygen Desaturation Increases Arterial Stiffness in Patients with COPD During the 6WMT.International journal of chronic obstructive pulmonary disease · 2024Trial
- Trial
- Association of cardio-ankle vascular index value with cardiovascular risk factors in elderly individuals.International journal of cardiology. Heart & vasculature · 2026Article
- Inconsistent associations between central and peripheral arterial stiffness indices in relation to age.Quantitative imaging in medicine and surgery · 2026Article
- Age-Related Associations of Blood Pressure and Arterial Stiffness with Retinal Arterial Structure.Ophthalmology science · 2026Article
- Hemodynamics and matrix stiffness shape the pathogenicity of SPP1Frontiers in immunology · 2026Review
- The Diagnostic Role of Novel Echocardiography Indices and Arterial Stiffness in Diabetic Cardiomyopathy.Biomedicines · 2025Article
- Hidden Cardiovascular Risk: Arterial Stiffness and Left Ventricular Remodeling as Potential Indicators of Masked Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2025Review
- Relationship between cardio-ankle vascular index value and stroke in hypertension patients cardio-ankle vascular index ≧9.PloS one · 2025Article
- Peripheral Hemodynamics Estimation Using the Photoplethysmography Method.Sensors (Basel, Switzerland) · 2024Article
- Cardio-Ankle Vascular Index: Test-Retest Reliability and Agreement in People With Stroke.Nursing & health sciences · 2024Article
- Relationship between the Mediterranean Diet and Vascular Function in Subjects with and without Increased Insulin Resistance.Nutrients · 2024Article
- Pulse Wave Velocity: Methodology, Clinical Applications, and Interplay with Heart Rate Variability.Reviews in cardiovascular medicine · 2024Review
- Association between the Serum Soluble Urokinase Plasminogen Activator Receptor and Peripheral Arterial Stiffness According to the Cardio-Ankle Vascular Index in Patients Undergoing Kidney Transplantation.Reviews in cardiovascular medicine · 2024Article
- Role of Vascular Function in the Prognosis of Heart Failure Patients.Journal of clinical medicine · 2024Article
- Association between Atherosclerosis and High-Risk Colorectal Adenomas based on Cardio-Ankle Vascular Index and Ankle-Brachial Index.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024Article
- Longitudinal Changes in Arterial Stiffness Associated with Physical Activity Intensity: The Toon Health Study.Journal of atherosclerosis and thrombosis · 2024Article
- Arterial Stiffness, Assessed Using the Cardio-Ankle Vascular Index, before and 2 Years after Total Knee Arthroplasty in Patients with Knee Osteoarthritis.Journal of clinical medicine · 2023Article
- Arterial Stiffness as a Surrogate Marker of Cardiovascular Disease and Atherosclerosis in Patients with Vasculitides: A Literature Review.Diagnostics (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Arterial stiffness is an age-related disorder. In the medial layer of arteries, mechanical fracture due to fatigue failure for the pulsatile wall strain causes medial degeneration vascular remodeling. The alteration of extracellular matrix composition and arterial geometry result in structural arterial stiffness. Calcium deposition and other factors such as advanced glycation end product-mediated collagen cross-linking aggravate the structural arterial stiffness. On the other hand, endothelial dysfunction is a cause of arterial stiffness. The biological molecular mechanisms relating to aging are known to involve the progression of arterial stiffness. Arterial stiffness further applies stress on large arteries and also microcirculation. Therefore, it is closely related to adverse outcomes in cardiovascular and cerebrovascular system. Cardio-ankle vascular index (CAVI) is a promising diagnostic tool for evaluating arterial stiffness. The principle is based on stiffness parameter β, which is an index intended to assess the distensibility of carotid artery. Stiffness parameter β is a two-dimensional technique obtained from changes of arterial diameter by pulse in one section. CAVI applied the stiffness parameter β to all of the arterial segments between heart and ankle using pulse wave velocity. CAVI has been commercially available for a decade and the clinical data of its effectiveness has accumulated. The characteristics of CAVI differ from other physiological tests of arterial stiffness due to the independency from blood pressure at the time of examination. This review describes the pathophysiology of arterial stiffness and CAVI. Molecular mechanisms will also be covered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.