Evidence map›Paper›PMID 31357440›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles.

Skyla A Duncan, Saurabh Dixit, Rajnish Sahu, David Martin, Dieudonné R Baganizi, Elijah Nyairo, Francois Villinger, Shree R Singh, Vida A Dennis

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Microencapsulation of a novelApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neuroprotective effects of interleukin 10 in spinal cord injury.Frontiers in molecular neuroscience · 2023
    Review
  12. Article
  13. Review
  14. Immune Responses to Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2021
    Article
  15. Article
  16. IL-10Frontiers in immunology · 2021
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Skyla A DuncanCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.ORCID 0000-0001-5640-1872
Saurabh DixitCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.
Rajnish SahuCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.ORCID 0000-0001-6270-2946
David MartinCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.
Dieudonné R BaganiziCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.
Elijah NyairoCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.
Francois VillingerNew Iberia Research Center, University of Louisiana at Lafayette, 4401 W Admiral Doyle Drive, New Iberia, LA 70560, USA.
Shree R SinghCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA.ORCID 0000-0002-3571-2222
Vida A DennisCenter for NanoBiotechnology & Life Sciences Research, Department of Biological Sciences, Alabama State University, 915 South Jackson Street, Montgomery, AL 36104, USA. vdennis@alasu.edu.
Alabama State University · USUniversity of Louisiana at Lafayette · US

Funding

RISE Option II:NIGMS-Research Initiative for Scientific Enhancement (RISE) Program at ASUR25GM106995 · NIGMS · ALABAMA STATE UNIVERSITY · PI DENNIS, VIDA A · 2013 to 2023
$3.0M
Mechanisms and protective efficacy of nanovaccines against Chlamydia trachomatisR21AI111159 · NIAID · ALABAMA STATE UNIVERSITY · PI DENNIS, VIDA A · 2014 to 2015
$341k
6 · The paper itself

Abstract

Inflammation, as induced by the presence of cytokines and chemokines, is an integral part of chlamydial infections. The anti-inflammatory cytokine, interleukin (IL)-10, has been reported to efficiently suppress the secretion of inflammatory cytokines triggered by

Indexed as

anti-inflammatorychlamydiacytokinesIL-10inflammationPLA-PEG nanoparticlesrecombinant major outer membrane protein (rMOMP)SOCS1SOCS3therapy

Identifiers

PMID31357440
PMCPMC6723354
OpenAlexW2963736543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.