Evidence map›Paper›PMID 31357427›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Structural Characterization and Digestibility of Curcumin Loaded Octenyl Succinic Nanoparticles.

Zhongshan Hu, Tao Feng, Xiaolan Zeng, Srinivas Janaswamy, Hui Wang, Osvaldo Campanella

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 37 citations in OpenAlex.

  1. Preparing O/W/O Emulsion for Curcumin (International journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhongshan HuSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, No. 100 Hai Quan Road, Shanghai 201418, China.
Tao FengSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, No. 100 Hai Quan Road, Shanghai 201418, China. fengtao@sit.edu.cn.ORCID 0000-0001-5582-4419
Xiaolan ZengSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, No. 100 Hai Quan Road, Shanghai 201418, China.
Srinivas JanaswamyDepartment of Dairy and Food Science, South Dakota State University, Brookings, SD 57007, USA.ORCID 0000-0002-5422-0493
Hui WangSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, No. 100 Hai Quan Road, Shanghai 201418, China.
Osvaldo CampanellaBiological Engineering and Whistler Carbohydrate Research Center, Philip E. Nelson Hall of Food Science, Room 2195745 Agricultural Mall, Purdue University, West Lafayette, IN 47906, USA.
Shanghai Institute of Technology · CNPurdue University West Lafayette · USSouth Dakota State University · US

Funding

China Tobacco Yunnan Industrial Corp TX2016002the USDA national Institute for Food and Agriculture (HATCH project SD00H648-18)
6 · The paper itself

Abstract

Curcumin displays anti-cancer, anti-inflammatory and anti-obesity properties but its water insolubility limits the wholesome utility. In this study, curcumin has been encapsulated in an amphiphilic biopolymer to enhance its water solubility. This was accomplished through self-assembly of octenyl succinic anhydride-short glucan chains (OSA-SGC) and curcumin. The nanoparticles were prepared with the degree of substitution (DS) of 0.112, 0.286 and 0.342 of OSA. Thus prepared nanoparticles were in the range of 150-200 nm and display high encapsulation efficiency and high loading capacity of curcumin. The Fourier-transform infrared (FTIR) and X-ray diffraction analyses confirmed the curcumin loading in the OSA-SGC nanoparticles. The complexes possessed a V-type starch structure. The thermo gravimetric analysis (TGA) revealed the thermal stability of encapsulated curcumin. The OSA-SGC nanoparticles greatly improved the curcumin release and dissolution, and in-turn promoted the sustained release.

Indexed as

amphiphilic biopolymercurcuminin vitro digestionoctenyl succinic anhydrideshort glucan chains

Identifiers

PMID31357427
PMCPMC6723743
OpenAlexW2963106742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.