Evidence map›Paper›PMID 31357423›Full record

ArticleInternational journal of molecular sciences2019

Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct

Jeffrey R Simmons, Alexandre Murza, Michael D Lumsden, Calem Kenward, Éric Marsault, Jan K Rainey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Determination of the pAnalytical chemistry · 2024
    Article
  2. Structure and Function of Membrane Proteins.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey R SimmonsDepartment of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Alexandre MurzaInstitut de Pharmacologie, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Michael D LumsdenDepartment of Chemistry, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Calem KenwardDepartment of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Éric MarsaultInstitut de Pharmacologie, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.
Jan K RaineyDepartment of Biochemistry & Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada. jan.rainey@dal.ca.ORCID 0000-0003-0793-5573

Funding

Canadian Institutes of Health Research 376770Canadian Institutes of Health Research MOP-111138Natural Sciences and Engineering Research Council of Canada 510963Nova Scotia Health Research Foundation MED-SSG-2015-10041
6 · The paper itself

Abstract

To probe ligand-receptor binding at the atomic-level, a frequent approach involves multidimensional nuclear magnetic resonance (NMR) spectroscopy experiments relying on

Indexed as

Fluorine-19 Magnetic Resonance ImagingLigandsMolecular ImagingAmino Acid SequenceApelin ReceptorsHumansMolecular StructureProtein BindingReceptors, G-Protein-CoupledStructure-Activity RelationshipApelin ReceptorsLigandsReceptors, G-Protein-Coupled19F-labelled apelin analogues19F NMRapelin receptor (APJ)G protein-coupled receptor (GPCR)ligand-receptor interactionspeptide-GPCR binding

Identifiers

PMID31357423
PMCPMC6696318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.