Evidence map›Paper›PMID 31357389›Full record

ArticleMolecules (Basel, Switzerland)2019

The Effect of Chitosan Derivatives on the Compaction and Tension Generation of the Fibroblast-populated Collagen Matrix.

K Tu Doan, Pratiksha Kshetri, Natthapume Attamakulsri, Derek R Newsome, Feifan Zhou, Cynthia K Murray, Wei R Chen, Gang Xu, Melville B Vaughan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

K Tu DoanCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Pratiksha KshetriCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Natthapume AttamakulsriCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Derek R NewsomeCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Feifan ZhouCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Cynthia K MurrayCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Wei R ChenCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Gang XuCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA.
Melville B VaughanCenter for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA. mvaughan4@uco.edu.ORCID 0000-0003-4648-6141
University of Central Oklahoma · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Mark L Lang · 2012 to 2026
$60.2M
NIGMS NIH HHS P20 GM103447NIH HHS P20GM103447NIH HHS R01CA205348-01NIH HHS RS20132225-106Oklahoma Center for the Advancement of Science and Technology HR16-085
6 · The paper itself

Abstract

Fibrotic diseases, such as Dupuytren's contracture (DC), involve excess scar tissue formation. The differentiation of fibroblasts into myofibroblasts is a significant mechanism in DC, as it generates tissue contraction in areas without wound openings, leading to the deposition of scar tissue, and eventually flexing one or more fingers in a restrictive fashion. Additionally, DC has a high recurrence rate. Previously, we showed that

Indexed as

Cell ProliferationCells, CulturedChitosanCollagenDupuytren ContractureExtracellular MatrixFibroblastsFibrosisHumansMyofibroblastsTomography, Optical CoherenceTransforming Growth Factor beta1ChitosanCollagenTransforming Growth Factor beta1chitosancollagen matrix contractionDupuytren’s ContracturefibrosismyofibroblastN-dihydrogalactochitosan (GC)optical coherence tomography

Identifiers

PMID31357389
PMCPMC6696429
OpenAlexW2963368719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.