Evidence map›Paper›PMID 31356900›Full record

ReviewNeuroscience2020

Tuning GABAergic Inhibition: Gephyrin Molecular Organization and Functions.

Rocco Pizzarelli, Marilena Griguoli, Paola Zacchi, Enrica Maria Petrini, Andrea Barberis, Antonino Cattaneo, Enrico Cherubini

Open access · hybridAbstract readReview
In one paragraph

Review in Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Cell-Intrinsic Regulation of Epilepsy-Associated Pathology by mTORC1 and mTORC2.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  6. Article
  7. Neuronal Calcium Signaling and Cytoskeletal Dynamics in Neurodegeneration.International journal of molecular sciences · 2026
    Review
  8. Molecular Physiology of the Neuronal Synapse.Current issues in molecular biology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rocco PizzarelliEuropean Brain Research Institute (EBRI), Fondazione Rita Levi-Montalcini, Roma, Italy.
Marilena GriguoliEuropean Brain Research Institute (EBRI), Fondazione Rita Levi-Montalcini, Roma, Italy.
Paola ZacchiDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Enrica Maria PetriniFondazione Istituto Italiano di Tecnologia (IIT), Department of Neuroscience and Brain Technologies, Plasticity of inhibitory networks Unit, Genoa, Italy.
Andrea BarberisFondazione Istituto Italiano di Tecnologia (IIT), Department of Neuroscience and Brain Technologies, Plasticity of inhibitory networks Unit, Genoa, Italy.
Antonino CattaneoEuropean Brain Research Institute (EBRI), Fondazione Rita Levi-Montalcini, Roma, Italy; Scuola Normale Superiore, Pisa, Italy.
Enrico CherubiniEuropean Brain Research Institute (EBRI), Fondazione Rita Levi-Montalcini, Roma, Italy; Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy. Electronic address: cher@sissa.it.
European Brain Research Institute · ITItalian Institute of Technology · ITScuola Internazionale Superiore di Studi Avanzati · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To be highly reliable, synaptic transmission needs postsynaptic receptors (Rs) in precise apposition to the presynaptic release sites. At inhibitory synapses, the postsynaptic protein gephyrin self-assembles to form a scaffold that anchors glycine and GABA

Indexed as

Membrane ProteinsSynapsesCarrier ProteinsHumansReceptors, GABA-ACarrier ProteinsgephyrinMembrane ProteinsReceptors, GABA-Agephyringlycine and GABA(A)Rsneuropsychiatric disordersstructural organizationsynaptic plasticity

Identifiers

PMID31356900
PMCPMC7351109
OpenAlexW2966533410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.