ArticlePLoS computational biology2019
Depressive symptoms are associated with blunted reward learning in social contexts.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 42 citations in OpenAlex.
- The Role of Alexithymia in Social Learning and Feedback-Driven Social Inferences.Computational psychiatry (Cambridge, Mass.) · 2026Article
- Advancing scientific understanding of the drive to socially engage: from broad constructs to transdiagnostic 'building blocks'.Molecular psychiatry · 2026Review
- Characterizing Transdiagnostic Processes Underlying the Drive to Socially Engage: A Multimeasurement Factor Analytic Investigation.JAACAP open · 2025Article
- A review of the effects of different types of social behaviors on the recruitment of neuropeptides and neurotransmitters in the nucleus accumbens.Frontiers in neuroendocrinology · 2025Review
- Reinforcement Learning and Decision Making in Depression in Adolescents and Young Adults: Insights from a New Model of the Probabilistic Reward Task.Computational psychiatry (Cambridge, Mass.) · 2025Article
- Beta activity in human anterior cingulate cortex mediates reward biases.Nature communications · 2024Article
- History of major depressive disorder is associated with differences in implicit learning of emotional faces.Journal of psychiatric research · 2023Article
- Computational models of subjective feelings in psychiatry.Neuroscience and biobehavioral reviews · 2023Review
- Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity.Neurobiology of stress · 2023Article
- Functioning of the EROS-R Scale in a Clinical Sample of Psychiatric Patients: New Psychometric Evidence from the Classical Test Theory and the Item Response Theory.International journal of environmental research and public health · 2022Article
- Article
- Challenging the negative learning bias hypothesis of depression: reversal learning in a naturalistic psychiatric sample.Psychological medicine · 2022Article
- Examining the Effectiveness of Gamification in Mental Health Apps for Depression: Systematic Review and Meta-analysis.JMIR mental health · 2021Review
- The actions of others act as a pseudo-reward to drive imitation in the context of social reinforcement learning.PLoS biology · 2020Article
- A Hierarchical Bayesian Implementation of the Experience-Weighted Attraction Model.Computational psychiatry (Cambridge, Mass.) · 2020Article
- Integration of social cues and individual experiences during instrumental avoidance learning.PLoS computational biology · 2020Article
- Negativity-bias in forming beliefs about own abilities.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is characterized by a marked decrease in social interactions and blunted sensitivity to rewards. Surprisingly, despite the importance of social deficits in depression, non-social aspects have been disproportionally investigated. As a consequence, the cognitive mechanisms underlying atypical decision-making in social contexts in depression are poorly understood. In the present study, we investigate whether deficits in reward processing interact with the social context and how this interaction is affected by self-reported depression and anxiety symptoms in the general population. Two cohorts of subjects (discovery and replication sample: N = 50 each) took part in an experiment involving reward learning in contexts with different levels of social information (absent, partial and complete). Behavioral analyses revealed a specific detrimental effect of depressive symptoms-but not anxiety-on behavioral performance in the presence of social information, i.e. when participants were informed about the choices of another player. Model-based analyses further characterized the computational nature of this deficit as a negative audience effect, rather than a deficit in the way others' choices and rewards are integrated in decision making. To conclude, our results shed light on the cognitive and computational mechanisms underlying the interaction between social cognition, reward learning and decision-making in depressive disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.