ArticleJournal of the Chinese Medical Association : JCMA2019
Perioperative blood transfusions are not associated with overall survival in elderly patients receiving surgery for fractured hips.
Article in Journal of the Chinese Medical Association : JCMA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Admission Hemoglobin Associated with Increased Mortality in Hip Fracture Surgical Patients: An Observational Study.Biomedicines · 2024Article
- Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15-Year Retrospective Cohort Study of 113 Cases.Orthopaedic surgery · 2023Article
- Preoperative risk factors for postoperative blood transfusion after hip fracture surgery: establishment of a nomogram.Journal of orthopaedic surgery and research · 2021Article
- Gender differences in blood transfusion strategy for patients with hip fractures - a retrospective analysis.International journal of medical sciences · 2020Observational
- The mortality and blood transfusion.Journal of the Chinese Medical Association : JCMA · 2020Article
- Reply to "The mortality and blood transfusion".Journal of the Chinese Medical Association : JCMA · 2020Article
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Abstract
backgroundWhether perioperative blood transfusions are associated with long-term outcomes remains controversial. This study aimed to evaluate the effect of blood transfusions on overall survival in hip fracture patients.
methodsThis retrospective survey was conducted at a single medical center and enrolled patients aged ≥ 70 years who received hip fracture surgery between 2013 and 2015. Multivariate Cox regression analysis was used to estimate the effect of blood transfusions on overall survival after surgery. Furthermore, patients who received a blood transfusion were further matched to those who did not receive a blood transfusion by patient characteristics. Stratified Cox regression analysis was used to assess the effect of transfusions on overall survival after matching.
resultsA total of 718 patients with a median follow-up period of 25.9 months were included in the analysis, of whom 495 (68.9%) received a blood transfusion. Four independent risk factors for mortality were identified, including male sex (hazard ratio [HR], 1.48; 95% CI, 1.01-2.17), aging (HR, 1.03; 95% CI, 1.0-1.06), general anesthesia (HR, 1.61; 95% CI, 1.11-2.31), and anemia status (mild vs no anemia: HR, 1.67; 95% CI, 0.96-2.90 and moderate versus no anemia: HR, 4.14; 95% CI, 2.35-7.3). The effect of blood transfusions on overall survival was nonsignificant after adjusting for the selected risk factors (HR, 1.44; 95% CI, 0.87-2.36). After matching, the effect of blood transfusions on overall survival remained nonsignificant (HR, 1.7; 95% CI, 0.78-3.71).
conclusionNo association was found between blood transfusions and overall survival among elderly patients undergoing hip fracture surgery. More prospective studies are necessary to elucidate the association between blood transfusions and long-term outcomes in patients receiving hip fracture surgery.
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