Evidence map›Paper›PMID 31356497›Full record

ArticleRetina (Philadelphia, Pa.)2020

POTENTIAL UTILITY OF FOVEAL MORPHOLOGY IN PRETERM INFANTS MEASURED USING HAND-HELD OPTICAL COHERENCE TOMOGRAPHY IN RETINOPATHY OF PREMATURITY SCREENING.

Samira Anwar, Mintu Nath, Aarti Patel, Helena Lee, Samantha Brown, Irene Gottlob, Frank A Proudlock

Open access · hybridAbstract read
In one paragraph

Article in Retina (Philadelphia, Pa.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Insights into the developing fovea revealed by imaging.Progress in retinal and eye research · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Samira AnwarUlverscroft Eye Unit, Robert Kilpatrick Clinical Sciences Building Leicester Royal Infirmary, University of Leicester, Leicester, United Kingdom.
Mintu NathDepartment of Cardiovascular Sciences, Glenfield Hospital, University of Leicester, Leicester, United Kingdom.
Aarti PatelUlverscroft Eye Unit, Robert Kilpatrick Clinical Sciences Building Leicester Royal Infirmary, University of Leicester, Leicester, United Kingdom.
Helena LeeDepartment of Ophthalmology, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton University Hospital, Southampton, United Kingdom; and.
Samantha BrownDepartment of Neonatology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Infirmary Square, Leicester, United Kingdom.
Irene GottlobUlverscroft Eye Unit, Robert Kilpatrick Clinical Sciences Building Leicester Royal Infirmary, University of Leicester, Leicester, United Kingdom.
Frank A ProudlockUlverscroft Eye Unit, Robert Kilpatrick Clinical Sciences Building Leicester Royal Infirmary, University of Leicester, Leicester, United Kingdom.
Leicester Royal Infirmary · GBUniversity of Leicester · GBUlverscroft (United Kingdom) · GBUniversity of Southampton · GB

Funding

Department of Health DRF-2014-07-136Medical Research Council MR/J004189/1Medical Research Council MR/N004566/1
6 · The paper itself

Abstract

purposeTo investigate dynamic foveal morphology with postmenstrual age, in preterm infants with and without retinopathy of prematurity using hand-held optical coherence tomography, adjusting for gestational age (GA) and birthweight (BW).

methodsProspective mixed cross-sectional/longitudinal observational study of 87 participants (23-36 weeks GA; n = 30 with, n = 57 without retinopathy of prematurity) using hand-held optical coherence tomography images (n = 278) acquired between 31 weeks and 44 weeks postmenstrual age excluding treated retinopathy of prematurity. Measurements included foveal width, area, depth, central foveal thickness, maximum slope, and parafoveal retinal thickness at 1,000 µm nasal and temporal to the central fovea.

resultsRetinopathy of prematurity was significantly correlated with only foveal width in either GA or BW adjusted statistical models. In contrast, severity of prematurity (GA, BW) correlated with foveal area (P < 0.005), depth (P ≤ 0.001), and slope (P < 0.01), although central foveal thickness (P = 0.007) and parafoveal retinal thickness (P < 0.001) correlated with GA, but not with BW.

conclusionFoveal width is independent of GA and BW with potential in retinopathy of prematurity screening assessment using hand-held optical coherence tomography. Foveal morphology could be graded in prematurity during development, with possible implications for future management of preterm infants.

Indexed as

Infant, PrematureTomography, Optical CoherenceBirth WeightCross-Sectional StudiesFemaleFovea CentralisGestational AgeHumansInfantInfant, NewbornMaleNeonatal ScreeningProspective StudiesRetinopathy of PrematurityVisual Acuity

Identifiers

PMID31356497
PMCPMC7392578
OpenAlexW2964017134

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.