ArticleAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)
Factors Predictive of Subretinal Fluid Resolution in Coats Disease: Analysis of 177 Eyes in 177 Patients at a Single Center.
Article in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Long-term outcome of Coats' disease: Implications for the classification of foveal vascular pathologies.Acta ophthalmologica · 2026Article
- Mapping Macrophage Diversity in Coats' Disease: A Lipid-Associated Subset in the Pathogenesis of Exudative Retinopathy.Investigative ophthalmology & visual science · 2025Article
- Place of dexamethasone implant as an adjunctive treatment in Coats' disease: a retrospective single-center study.BMC ophthalmology · 2025Article
- Coats' disease - Prognostic factors for globe and vision salvage in children, a long-term experience.Indian journal of ophthalmology · 2022Article
- Idiopathic Peripheral Retinal Telangiectasia in Adults: A Case Series and Literature Review.Journal of clinical medicine · 2021Article
- Coats disease in 351 eyes: Analysis of features and outcomes over 45 years (by decade) at a single center.Indian journal of ophthalmology · 2019Article
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Abstract
purposeThe aim of this study was to investigate factors predictive of subretinal fluid (SRF) resolution in Coats disease.
designRetrospective cohort study.
methodsInstitutional review board-approved review of patients diagnosed with Coats disease demonstrating SRF (stage 3-5) at a single center from November 1973 to July 2018 with comparison of eyes that had resolution of SRF to those in which SRF persisted.
resultsThere were 177 cases (154 males, 87%) of Coats disease diagnosed at a mean age of 8 years. After a mean follow-up of 62 months, SRF resolved in 110 (62%) and persisted in 67 (38%) eyes. Comparison (resolved SRF vs persistent SRF) revealed classification as stage 3A [63 (57%) vs 20 (29%)], stage 3B [47 (43%) vs 40 (60%)], or stage 4 [0 (0%) vs 7 (11%)] (P < 0.001). Eyes with resolved SRF presented with fewer clock hours of telangiectasia (mean: 5 vs 7 clock hours, P < 0.001), light bulb aneurysms (mean: 5 vs 7 clock hours, P < 0.001), exudation (mean: 7 vs 10 clock hours, P < 0.001), and extent of SRF (mean: 7 vs 10 clock hours, P < 0.001). Factors predictive of SRF resolution included absence of iris neovascularization on fluorescein angiography [odds ratio 0.05 (95% confidence interval 0.01-0.60), P = 0.02], and less elevated SRF by ultrasonography [odds ratio 0.84 (95% confidence interval 0.76-0.95), P = 0.004). For every 1-mm decrease in SRF, likelihood of SRF resolution increased by 16%.
conclusionsResolution of SRF was achieved in the majority of eyes (62%) with stage 3 to 5 Coats disease. Predictors of SRF resolution included lack of neovascularization on fluorescein angiography and less elevation of SRF by ultrasonography.
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