Evidence map›Paper›PMID 31356272›Full record

SynthesisAnnals of surgery2020

The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis.

Victor X Fu, Pim Oomens, Markus Klimek, Michiel H J Verhofstad, Johannes Jeekel

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06286137 nacompletednot on this mapstarted 2024, after this paper: background citation

Duration of Music Interventions and PAiN Tolerance in Healthy Individuals: the DOMINANT Trial

TypeinterventionalSponsorErasmus Medical CenterRan2024 to 2024Enrolled80ConditionsPain, AcuteArmsListening to music for 1 minute, Listening to music for 5 minutes, Listening to music for 20 minutes, Not listening to music
NCT07687095 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Intraoperative Music on Propofol Consumption and BIS Values in Patients Undergoing Elective Breast Surgery: A Randomized Controlled Trial

TypeinterventionalSponsorUludag UniversityRan2026 to 2027Enrolled74ConditionsAnesthesia , Analgesia, Breast SurgeryArmsIntraoperative Music
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victor X FuDepartment of Surgery, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
Pim OomensDepartment of Surgery, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
Markus KlimekDepartment of Anesthesiology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
Michiel H J VerhofstadDepartment of Surgery, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
Johannes JeekelDepartment of Neuroscience, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess and quantify the effect of perioperative music on medication requirement, length of stay and costs in adult surgical patients. SUMMARY BACKGROUND DATA: There is an increasing interest in nonpharmacological interventions to decrease opioid analgesics use, as they have significant adverse effects and opioid prescription rates have reached epidemic proportions. Previous studies have reported beneficial outcomes of perioperative music.

methodsA systematic literature search of 8 databases was performed from inception date to January 7, 2019. Randomized controlled trials investigating the effect of perioperative music on medication requirement, length of stay or costs in adult surgical patients were eligible. Meta-analysis was performed using random effect models, pooled standardized mean differences (SMD) were calculated with 95% confidence intervals (CI). This study was registered with PROSPERO (CRD42018093140) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines.

resultsThe literature search yielded 2414 articles, 55 studies (N = 4968 patients) were included. Perioperative music significantly reduced postoperative opioid requirement (pooled SMD -0.31 [95% CI -0.45 to -0.16], P < 0.001, I = 44.3, N = 1398). Perioperative music also significantly reduced intraoperative propofol (pooled SMD -0.72 [95% CI -1.01 to -0.43], P < 0.00001, I = 61.1, N = 554) and midazolam requirement (pooled SMD -1.07 [95% CI -1.70 to -0.44], P < 0.001, I = 73.1, N = 184), while achieving the same sedation level. No significant reduction in length of stay (pooled SMD -0.18 [95% CI -0.43 to 0.067], P = 0.15, I = 56.0, N = 600) was observed.

conclusionsPerioperative music can reduce opioid and sedative medication requirement, potentially improving patient outcome and reducing medical costs as higher opioid dosage is associated with an increased risk of adverse events and chronic opioid abuse.

Indexed as

Music TherapyAnalgesics, OpioidHumansHypnotics and SedativesLength of StayPerioperative PeriodPostoperative PainRandomized Controlled Trials as TopicAnalgesics, OpioidHypnotics and Sedatives

Identifiers

PMID31356272
PMCPMC7668322

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.