Evidence map›Paper›PMID 31356168›Full record

ArticleImmunoHorizons2019

Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function during Influenza A Virus Infection.

Anthony M Franchini, Jason R Myers, Guang-Bi Jin, David M Shepherd, B Paige Lawrence

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. When AHR signaling pathways meet viral infections.Cell communication and signaling : CCS · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anthony M FranchiniDepartment of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642.ORCID 0000-0003-3576-3211
Jason R MyersGenomics Research Center, James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642.ORCID 0000-0002-0341-0860
Guang-Bi JinDepartment of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642.ORCID 0000-0001-6197-7171
David M ShepherdDepartment of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT 59812; and.ORCID 0000-0003-4334-9715
B Paige LawrenceDepartment of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; paige_lawrence@urmc.rochester.edu.ORCID 0000-0003-4882-9750
University of Rochester · USUniversity of Montana · USUniversity of Rochester Medical Center · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Sally W Thurston · 1985 to 2026
$42.8M
Training in Environment ToxicologyT32ES007026 · NIEHS · UNIVERSITY OF ROCHESTER · PI Alison Elder, Marissa Sobolewski Terry · 1985 to 2026
$20.2M
TCDD EFFECT ON T LYMPHOCYTE DIFFERENTIATIONR01ES004862 · NIEHS · UNIVERSITY OF ROCHESTER · PI LAWRENCE, B PAIGE · 1990 to 2020
$6.5M
Development of a novel platform for the delivery of AhR antagonists to DCs and T cellsR01ES013784 · NIEHS · UNIVERSITY OF MONTANA · PI SHEPHERD, DAVID M · 2006 to 2017
$4.0M
Transgenerational exposures as modifiers of host defense against infectionR01ES023260 · NIEHS · UNIVERSITY OF ROCHESTER · PI LAWRENCE, B PAIGE · 2013 to 2017
$3.0M
NIEHS NIH HHS P30 ES001247NIEHS NIH HHS R01 ES004862NIEHS NIH HHS R01 ES013784NIEHS NIH HHS R01 ES023260NIEHS NIH HHS T32 ES007026
6 · The paper itself

Abstract

Activation of the ligand inducible aryl hydrocarbon receptor (AhR) during primary influenza A virus infection diminishes host responses by negatively regulating the ability of dendritic cells (DC) to prime naive CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCell Adhesion MoleculesCell DifferentiationChemokine CCL17Cytotoxicity, ImmunologicDC-Specific ICAM-3 Grabbing NonintegrinDendritic CellsGenomeImmune EvasionInfluenza A virusLectins, C-TypeLungLymphocyte ActivationMiceMice, Inbred C57BLCell Adhesion MoleculesChemokine CCL17DC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypePolychlorinated DibenzodioxinsReceptors, Aryl HydrocarbonReceptors, Cell Surface

Identifiers

PMID31356168
PMCPMC6953410
OpenAlexW2952092983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.