Evidence map›Paper›PMID 31355997›Full record

ArticleJournal of applied clinical medical physics2019

Deformable abdominal phantom for the validation of real-time image guidance and deformable dose accumulation.

Charles K Matrosic, Jennifer Hull, Benjamin Palmer, Wesley Culberson, Bryan Bednarz

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. 3D dosimetric validation of ultrasound-guided radiotherapy with a dynamically deformable abdominal phantom.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Charles K MatrosicSchool of Medicine and Public Health, Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jennifer HullSchool of Medicine and Public Health, Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Benjamin PalmerSchool of Medicine and Public Health, Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Wesley CulbersonSchool of Medicine and Public Health, Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Bryan BednarzSchool of Medicine and Public Health, Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Wisconsin Division of Public Health · USUniversity of Wisconsin–Madison · US

Funding

Real-time Tumor Localization and Guidance for Radiotherapy Using US and MRIR01CA190298 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BEDNARZ, BRYAN PATRICK, FOO, THOMAS K · 2015 to 2019
$3.1M
NCI NIH HHS R01 CA190298NIH HHS R01CA190298
6 · The paper itself

Abstract

purposeEnd-to-end testing with quality assurance (QA) phantoms for deformable dose accumulation and real-time image-guided radiotherapy (IGRT) has recently been recommended by American Association of Physicists in Medicine (AAPM) Task Groups 132 and 76. The goal of this work was to develop a deformable abdominal phantom containing a deformable three-dimensional dosimeter that could provide robust testing of these systems.

methodsThe deformable abdominal phantom was fabricated from polyvinyl chloride plastisol and phantom motion was simulated with a programmable motion stage and plunger. A deformable normoxic polyacrylamide gel (nPAG) dosimeter was incorporated into the phantom apparatus to represent a liver tumor. Dosimeter data were acquired using magnetic resonance imaging (MRI). Static measurements were compared to planned dose distributions. Static and dynamic deformations were used to simulate inter- and intrafractional motion in the phantom and measurements were compared to baseline measurements.

resultsThe statically irradiated dosimeters matched the planned dose distribution with an average γ pass rates of 97.0 ± 0.5% and 97.5 ± 0.2% for 3%/5 mm and 5%/5 mm criteria, respectively. Static deformations caused measured dose distribution shifts toward the phantom plunger. During the dynamic deformation experiment, the dosimeter that utilized beam gating showed an improvement in the γ pass rate compared to the dosimeter that did not.

conclusionsA deformable abdominal phantom apparatus which incorporates a deformable nPAG dosimeter was developed to test real-time IGRT systems and deformable dose accumulation algorithms. This apparatus was used to benchmark simple static irradiations in which it was found that measurements match well to the planned distributions. Deformable dose accumulation could be tested by directly measuring the shifts and blurring of the target dose due to interfractional organ deformation and motion. Dosimetric improvements were achieved from the motion management during intrafractional motion.

Indexed as

Phantoms, ImagingAbdomenAlgorithmsComputer SimulationHumansImage Processing, Computer-AssistedNeoplasmsRadiometryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedDeformable dose accumulationmotion managementphantomsthree-dimensional dosimetry

Identifiers

PMID31355997
PMCPMC6698755
OpenAlexW2965325939

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.