ArticleAmerican journal of clinical pathology2019
Metastatic Basal Cell Carcinoma.
Article in American journal of clinical pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Margins in head and neck non-melanoma skin cancer surgery: clinical/pathological criteria and their impact on oncological outcomes and therapeutic choices. A systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Pooled it
- Metastatic Basal Cell Carcinoma With Unusual Molecular Genetics Findings.Clinical case reports · 2026Article
- Dark Skin Evolution in Early Humans: Revisiting the Skin Cancer Hypothesis Through Migration-Related Mismatch.Molecular biology and evolution · 2026Review
- Clinical Features and Outcomes of Locally Advanced and Metastatic Basal Cell Carcinoma.Acta dermato-venereologica · 2025Article
- Minimizing Surgical Margins in Basal Cell Carcinoma: A Single Institution's Experience with Excision and Reconstruction Methods.Archives of plastic surgery · 2025Article
- GATA3 Positively Correlates with BCL2 Expression in Indolent and Aggressive Histological Types of Cutaneous Basal Cell Carcinoma.Turk patoloji dergisi · 2024Article
- Immunotherapy and Its Timing in Advanced Basal Cell Carcinoma Treatment.Dermatology practical & conceptual · 2023Review
- Review
- Basosquamous Basal Cell Carcinoma with Bone Marrow Metastasis.Current oncology (Toronto, Ont.) · 2022Article
- Article
- Neglected cutaneous skin malignancy: A patient with concurrent giant basal cell carcinoma and melanoma.Skin health and disease · 2021Article
- Metastatic basal cell carcinoma with atypical pattern of spread.Radiology case reports · 2020Article
- Erosive rodent ulcer of the ear secondary to neglect.BMJ case reports · 2020Article
- The Pathobiology of Skin Aging: New Insights into an Old Dilemma.The American journal of pathology · 2020Review
- Personalized treatment concepts in extraocular cancer.Advances in ophthalmology practice and researchReview
- Statical Association between Clinical and Histopathological Parameters for Keratinocyte Carcinomas.Current health sciences journalArticle
- A Rare Case of Neglected Giant Basal Cell Carcinoma in a Nurse-Case Report and Literature Review.Current health sciences journalArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesDiagnosis of metastatic basal cell carcinoma (BCC) remains challenging, in part due to its rarity. With the advent of molecularly targeted therapies, recognition of this entity is more important than ever.
methodsWe identified 11 cases of metastatic BCC over a 13-year period. We analyzed these tumors in conjunction with their respective primary tumors by histomorphologic, immunohistochemical, and molecular genetic analyses.
resultsWe identified three morphologic patterns of metastasis in BCC. The most common (seven cases) was characterized by completely typical features of BCC. Two cases showed marked squamous differentiation within BCC. The final two cases showed exclusively features of a poorly differentiated carcinoma. One of these was definitively classified by molecular analysis, as both the primary and metastatic tumors harbored the same inactivating PTCH1 mutation.
conclusionsThis study illustrates multiple distinct morphologic patterns in metastatic BCC and highlights the utility of ancillary molecular testing for accurate diagnosis.
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