Evidence map›Paper›PMID 31355824›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2019

Epidemiology of

Y Xia, M C Tunis, C Frenette, K Katz, K Amaratunga, S Rhodenizer Rose, A House, C Quach

Abstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Epidemiologic profile of community-acquiredEpidemiology and infection · 2025
    Pooled it
  2. Diagnosis, treatment, and prophylaxis ofJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026
    Article
  3. Changes in the Epidemiology of Clostridioides difficile Infection.Infectious disease clinics of North America · 2025
    Review
  4. Surveillance for Health Care-Associated Infections, Antimicrobial Resistant Organisms and Antimicrobial use in Canadian Long-Term Care Homes: A Cross-Sectional Survey.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Microorganisms · 2023
    Article
  11. Retrospective Cohort Analysis of Outpatient Antibiotic Use forThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  12. Detection and Genomic Characterisation ofPathogens (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Divergences between healthcare-associated infection administrative data and active surveillance data in Canada.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  15. Article
  16. Initial vancomycin versus metronidazole for the treatment of first-episode non-severeAntimicrobial stewardship & healthcare epidemiology : ASHE · 2021
    Article
  17. Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2014-2018.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Y XiaDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC.
M C TunisCentre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.
C FrenetteDepartment of Laboratory Medicine, McGill University Health Centre, Montreal, QC.
K KatzNorth York General Hospital, Toronto, ON.
K AmaratungaCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
S Rhodenizer RoseInfection Prevention and Control Canada, Halifax, NS.
A HouseCentre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.
C QuachDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo vaccines against

objectivesTo determine the epidemiology of hospital-acquired CDI (HA-CDI) and community-associated CDI (CA-CDI) in Canada using provincial surveillance data and document discrepancies in CDI-related definitions among provincial surveillance programs.

methodsPublicly-available CDI provincial surveillance data from 2011 to 2016 that distinguished between HA-CDI and CA-CDI were included and the most common surveillance definitions for each province were used. The HA-, CA-CDI incidence rates and CA-CDI proportions (%) were calculated for each province. Both HA- and CA-CDI incidence rates were examined for trends. Types of disparities were summarized and detailed discrepancies were documented.

resultsCanadian data were analyzed from nine provinces. The HA-CDI rates ranged from 2.1/10,000 to 6.5/10,000 inpatient-days, with a decreasing trend over time. Available data on CA-CDI showed that both rates and proportions have been increasing over time. Discrepancies among provincial surveillance definitions were documented in CDI case classifications, surveillance populations and rate calculations.

conclusionIn Canada overall, the rate of HA-CDI has been decreasing and the rate of CA-CDI has been increasing, although this calculation was impeded by discrepancies in CDI-related definitions among provincial surveillance programs. Nationally-adopted common definitions for CDI would enable better comparisons of CDI rates between provinces and a calculation of the pan-Canadian burden of illness to support vaccine decision-making.

Indexed as

burden of illnessC. difficiledefinitionsepidemiologysurveillancevaccine

Identifiers

PMID31355824
PMCPMC6615439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.