Evidence map›Paper›PMID 31355526›Full record

ArticleCancer medicine2019

Effect of IDH3a on glucose uptake in lung adenocarcinoma: A pilot study based on [

Bulin Du, Tong Sun, Xuena Li, Yao Diao, Yaming Li

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1-JUN/FOS Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Molecular Insights into BZW1 Expression and [Molecular imaging and biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bulin DuDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, Liaoning, China.ORCID https://orcid.org/0000-0002-9368-9200
Tong SunDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Xuena LiDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Yao DiaoDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Yaming LiDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, Liaoning, China.
First Hospital of China Medical University · CN

Funding

National Natural Science Foundation of China 81771867National Natural Science Foundation of China 81771868Young Scholars Program of China Medical University QGZ-2018036
6 · The paper itself

Abstract

Subunit of isocitrate dehydrogenase 3 (IDH3a) as upstream of the hypoxia-inducible factor was reported highly expressed in malignant tumors, playing an important role in glucose metabolism reprogramming. As one of rate-limiting enzyme in the Krebs cycle, whether high expression of IDH3a affects glucose uptake in tumors has not been elucidated. This study was aimed to investigate the relationship between IDH3a expression and tumor glucose uptake. Sixty-five patients who underwent 2-[

Indexed as

Adenocarcinoma of LungAgedBiological TransportBiomarkersCell Line, TumorFemaleFluorodeoxyglucose F18Gene ExpressionGlucoseGlucose Transporter Type 1HumansImmunohistochemistryIsocitrate DehydrogenaseMaleMiddle AgedPilot ProjectsBiomarkersFluorodeoxyglucose F18GlucoseGlucose Transporter Type 1IDH3A protein, humanIsocitrate Dehydrogenase2-[18F]-2-deoxy-D-glucoseisocitrate dehydrogenaselung adenocarcinomapositron emission tomography

Identifiers

PMID31355526
PMCPMC6718547
OpenAlexW2966659221

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.