Evidence map›Paper›PMID 31355354›Full record

ArticleJournal of psoriasis and psoriatic arthritis2018

Pediatric psoriatic arthritis: a population-based cohort study of risk factors for onset and subsequent risk of inflammatory comorbidities.

Timothy G Brandon, Cynthia K Manos, Rui Xiao, Alexis Ogdie, Pamela F Weiss

Open access · greenAbstract read
In one paragraph

Article in Journal of psoriasis and psoriatic arthritis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. MRI Findings in Axial Psoriatic Spondylarthritis.Diagnostics (Basel, Switzerland) · 2023
    Review
  14. Review
  15. Psoriasis and Systemic Inflammatory Disorders.International journal of molecular sciences · 2022
    Review
  16. Article
  17. New Insights on Juvenile Psoriatic Arthritis.Frontiers in pediatrics · 2022
    Review
  18. Article
  19. Management of psoriasis in children (Review).Experimental and therapeutic medicine · 2021
    Review
  20. Recommendations for Management of Childhood Psoriasis.Indian dermatology online journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Timothy G BrandonDivision of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Cynthia K ManosDivision of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Rui XiaoDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Alexis OgdieCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania.
Pamela F WeissDivision of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Children's Hospital of Philadelphia · USHospital of the University of Pennsylvania · USUniversity of Pennsylvania · US

Funding

Identification of Early Psoriatic ArthritisK23AR063764 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI OGDIE, ALEXIS R. · 2013 to 2017
$751k
Refining Outcome Measurement in Psoriatic Arthritis: Preparation for Pragmatic TrialsR01AR072363 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI OGDIE, ALEXIS R. · 2017 to 2019
$709k
Evaluation and treatment of enthesitis-related arthritisK23AR059749 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI WEISS, PAMELA FITCH · 2011 to 2015
$610k
NIAMS NIH HHS K23 AR059749NIAMS NIH HHS K23 AR063764NIAMS NIH HHS L30 AR060070NIAMS NIH HHS R01 AR072363
6 · The paper itself

Abstract

backgroundRelatively little is known about the epidemiology of juvenile psoriatic arthritis (PsA), including clinical features associated with the development of arthritis among children with psoriasis and subsequent risk of inflammatory comorbidities.

objectiveTo identify the overall risk of arthritis among children with psoriasis and subsequent risk of inflammatory comorbidities.

methodsUsing Clinformatics™ DataMart (OptumInsight, Eden Prairie, MN) de-identified US administrative claims data from 2000-2013, we identified children 0-16 years with an incident diagnosis of psoriasis or PsA using ICD-9-CM diagnostic, procedure and pharmacy billing codes. Cox proportional hazard regression was performed to assess clinical features associated with development of arthritis in children with psoriasis. Incidence rate ratios were used to compare the relative frequency of co-morbid diagnoses.

resultsWe identified 212 children with PsA, 4,312 with psoriasis-only, and 45,240 controls. Approximately 33% of children with PsA received a diagnostic code for psoriasis before arthritis. Median time to index code for arthritis after index code for psoriasis was 17.6 months (IQR 4.1-38.1). Older age and uveitis were associated with a significantly increased risk of developing arthritis in children with psoriasis. Children with PsA had a significantly increased risk of uveitis, diabetes, and depressive disorder when compared to patients with psoriasis and inflammatory bowel disease, uveitis, diabetes, and depressive disorder when compared to controls.

conclusionMost children with PsA developed arthritis first. Older age and uveitis were risk factors for arthritis among children with psoriasis. PsA was associated with increased risk of several clinically relevant inflammatory comorbidities.

Indexed as

ComorbidityDiagnosisPediatricPsoriasisPsoriatic Arthritis

Identifiers

PMID31355354
PMCPMC6660180
OpenAlexW2890336658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.