ArticleScience advances2019
Bioinspired mechanically active adhesive dressings to accelerate wound closure.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
137 citing papers in PubMed, 1 synthesis or guideline pooled it, 518 citations in OpenAlex.
- The Functional Role of Interface Tissue Engineering in Annulus Fibrosus Repair: Bridging Mechanisms of Hydrogel Integration with Regenerative Outcomes.ACS biomaterials science & engineering · 2020Pooled it
- Contractile hydrogel with NIR-induced spatiotemporally programmed release from core-shell nanoparticles for integrated antibacterial and pro-angiogenic healing.Materials today. Bio · 2026Article
- Bioadhesive Hydrogels for Tissue Repair: Design Strategies, Adhesion Mechanisms, and Emerging Applications.Molecules (Basel, Switzerland) · 2026Review
- Next-Generation Hydrogel Skin Adhesives: From Bioinspired Adhesion Chemistry to Regenerative Wound Interfaces.Advanced healthcare materials · 2026Review
- Mechanically Active Contractile Hydrogels for Skin Wound Repair.Gels (Basel, Switzerland) · 2026Review
- Mechanically Active Adhesive Hydrogels Driven by Peptide Self-Assembly for Accelerated Healing of Diverse Wounds.Advanced healthcare materials · 2026Article
- Gold nanocluster-complexed dressings for instant closure of bacteria-infected wound.Journal of nanobiotechnology · 2026Article
- Machine learning-guided design of mechanoadaptive bioglues for multitissue trauma and first-aid applications.Nature biomedical engineering · 2026Article
- Thermosensitive citrate-based mussel-inspired attack-defense integrated bioadhesives facilitate complicated wound healing.Bioactive materials · 2026Article
- Seta-Inspired Mechano-Intelligent Janus Bandage with Coordinated Adhesion-Contraction for Minimizing Scarring.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Near-infrared light-driven photocatalytic reactive oxygen species-generating antibacterial and self-shrinking hybrid hydrogels for combating drug-resistant bacterial biofilm infection and accelerating wound healing.Bioactive materials · 2026Article
- A Multifunctional Shape-Adaptive Bilayer Hydrogel for Acute Hemostasis, Wound Repair, and Insect Bite Defense.Gels (Basel, Switzerland) · 2026Article
- Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A WR3-NHMaterials today. Bio · 2026Article
- A thermogalvanic cell dressing for smart wound monitoring and accelerated healing.Nature biomedical engineering · 2026Article
- Nano-Engineered Dressings for Infected Diabetic Wounds: Synergy of Catalysis, Delivery, and Fluid Management.International journal of nanomedicine · 2026Review
- Engineering a cell wall-deficient protoplast-incorporated hydrogel for infected wound healing.Regenerative biomaterials · 2026Article
- Hydrogels for Analyte Sensing.ACS measurement science au · 2025Review
- Exploring bioadhesion: insight on innovative strategies to investigate bioadhesive scaffolds.International journal of pharmaceutics: X · 2025Review
- Point-of-care treatment of acute skin wound by portable in-situ electrospinning nanofiber dressings with rapid hemostasis, anti-infection, and angiogenesis effects.Bioactive materials · 2025Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Inspired by embryonic wound closure, we present mechanically active dressings to accelerate wound healing. Conventional dressings passively aid healing by maintaining moisture at wound sites. Recent developments have focused on drug and cell delivery to drive a healing process, but these methods are often complicated by drug side effects, sophisticated fabrication, and high cost. Here, we present novel active adhesive dressings consisting of thermoresponsive tough adhesive hydrogels that combine high stretchability, toughness, tissue adhesion, and antimicrobial function. They adhere strongly to the skin and actively contract wounds, in response to exposure to the skin temperature. In vitro and in vivo studies demonstrate their efficacy in accelerating and supporting skin wound healing. Finite element models validate and refine the wound contraction process enabled by these active adhesive dressings. This mechanobiological approach opens new avenues for wound management and may find broad utility in applications ranging from regenerative medicine to soft robotics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.