Evidence map›Paper›PMID 31355279›Full record

ArticleBioMed research international2019

Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat.

Yu Feng, Yan Chen, Binrui Yang, Qingping Lan, Tao Wang, Guozhen Cui, Zhitao Ren, I Cheong Choi, George Pak-Heng Leung, Fenggen Yan and 3 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  8. Overview ofAntioxidants (Basel, Switzerland) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Yu FengState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.
Yan ChenState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.
Binrui YangState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.ORCID https://orcid.org/0000-0003-2160-2273
Qingping LanState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.
Tao WangDepartment of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, China.
Guozhen CuiState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.ORCID https://orcid.org/0000-0002-7639-2456
Zhitao RenState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.
I Cheong ChoiDepartment of Gastroenterology, Kiang Wu Hospital, Macau.
George Pak-Heng LeungDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong.
Fenggen YanThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.
Dacan ChenThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-7300-194X
Hon Ho YuDepartment of Gastroenterology, Kiang Wu Hospital, Macau.ORCID https://orcid.org/0000-0002-9580-345X
Simon Ming Yuen LeeState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macau.ORCID https://orcid.org/0000-0002-3966-6569
University of Macau · MOGuangzhou University of Chinese Medicine · CNKiang Wu Hospital · CNZunyi Medical University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In parallel with the prevalence metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in most countries. It features a constellation of simple steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and even hepatocellular carcinoma. There are no approved drugs for effective management of NAFLD and NASH. Jianpi Huoxue formula (JPHX) mainly consists of Atractylodes macrocephal

Indexed as

LiverNon-alcoholic Fatty Liver DiseaseAnimalsCholineDrugs, Chinese HerbalFood, FormulatedMaleMethionineRatsRats, WistarCholineDrugs, Chinese HerbalJianpi Huoxue decoctionMethionine

Identifiers

PMID31355279
PMCPMC6634080
OpenAlexW2953813737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.