Evidence map›Paper›PMID 31355263›Full record

ReviewBioMed research international2019

Evaluation of Task-Related Brain Activity: Is There a Role for

Agostino Chiaravalloti, Alessandro Micarelli, Maria Ricci, Marco Pagani, Gabriele Ciccariello, Ernesto Bruno, Marco Alessandrini, Orazio Schillaci

Abstract readReview
In one paragraph

Review in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Cognitive benefits of sleep: a narrative review to explore the relevance of glucose regulation.Sleep advances : a journal of the Sleep Research Society · 2025
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agostino ChiaravallotiDepartment of Biomedicine and Prevention, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.ORCID https://orcid.org/0000-0002-8017-8858
Alessandro MicarelliDepartment of Clinical Sciences and Translational Medicine, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.ORCID https://orcid.org/0000-0002-0495-5272
Maria RicciDepartment of Radiological, Oncological and Pathological Sciences, Faculty of Medicine and Surgery, La Sapienza University, Rome, Italy.
Marco PaganiInstitute of Cognitive Sciences and Technologies, CNR, Rome, Italy.
Gabriele CiccarielloIRCCS Neuromed, UOC Medicina Nucleare, Pozzilli (IS), Italy.
Ernesto BrunoDepartment of Clinical Sciences and Translational Medicine, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.
Marco AlessandriniDepartment of Clinical Sciences and Translational Medicine, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.ORCID https://orcid.org/0000-0001-9955-6890
Orazio SchillaciDepartment of Biomedicine and Prevention, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) with 2-[18F]-fluorodeoxyglucose (FDG) has been widely used for the evaluation of cortical glucose metabolism in several neurodegenerative disorders while its potential role in the evaluation of cortical and subcortical activity during a task in the healthy and pathological brain still remains to be a matter of debate. Few studies have been carried out in order to investigate the potential role of this radiotracer for the evaluation of brain glucose consumption during dynamic brain activation. The aim of this review is to provide a general overview of the applications of FDG-PET in the evaluation of cortical activation at rest and during tasks, describing first the physiological basis of FDG distribution in brain and its kinetic in vivo. An overview of the imaging protocols and image interpretation will be provided as well. As a last aspect, the results of the main studies in this field will be summarized and the results of PET findings performed in healthy subjects and patients suffering from various diseases will be reported.

Indexed as

Cerebral CortexNeurodegenerative DiseasesPositron-Emission TomographyFluorodeoxyglucose F18HumansRadiopharmaceuticalsFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID31355263
PMCPMC6634077

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.