Evidence map›Paper›PMID 31355179›Full record

ArticleFrontiers in chemistry2019

Design, Synthesis, and Biological Evaluation of (E)-N'-((1-Chloro-3,4-Dihydronaphthalen-2-yl)Methylene)Benzohydrazide Derivatives as Anti-prostate Cancer Agents.

H A Arjun, Ramakrishnan Elancheran, N Manikandan, K Lakshmithendral, Muthiah Ramanathan, Atanu Bhattacharjee, N K Lokanath, Senthamaraikannan Kabilan

RetractedErratum issuedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

H A ArjunDrug Discovery Lab, Department of Chemistry, Annamalai University, Chidambaram, India.
Ramakrishnan ElancheranDrug Discovery Lab, Department of Chemistry, Annamalai University, Chidambaram, India.
N ManikandanDepartment of Pharmacology, PSG College of Pharmacy, Coimbatore, India.
K LakshmithendralDrug Discovery Lab, Department of Chemistry, Annamalai University, Chidambaram, India.
Muthiah RamanathanDepartment of Pharmacology, PSG College of Pharmacy, Coimbatore, India.
Atanu BhattacharjeeComputational Biology Laboratory, Department of Biotechnology & Bioinformatics, North Eastern Hill University, Shillong, India.
N K LokanathDepartment of Physics, University of Mysore, Mysore, India.
Senthamaraikannan KabilanDrug Discovery Lab, Department of Chemistry, Annamalai University, Chidambaram, India.
Annamalai University · INNorth Eastern Hill University · INUniversity of Mysore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate Cancer (PCa) is the most frequently diagnosed cancer in men in their late '50s. PCa growth is mainly due to the activation of the androgen receptor by androgens. The treatment for PCa may involve surgery, hormonal therapy, and oral chemotherapeutic drugs. A structural based molecular docking approach revealed the findings of

Indexed as

ADMEandrogen receptorbenzohydrazidemolecular dockingmolecular dynamicsprostate cancer

Identifiers

PMID31355179
PMCPMC6636335
OpenAlexW2960916145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.