Evidence map›Paper›PMID 31355153›Full record

ArticleFrontiers in cellular and infection microbiology2019

Thymic Microenvironment Is Modified by Malnutrition and

Monica Losada-Barragán, Adriana Umaña-Pérez, Jonathan Durães, Sergio Cuervo-Escobar, Andrés Rodríguez-Vega, Flávia L Ribeiro-Gomes, Luiz R Berbert, Fernanda Morgado, Renato Porrozzi, Daniella Arêas Mendes-da-Cruz and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Frontiers in immunology · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Infection-Associated Thymic Atrophy.Frontiers in immunology · 2021
    Review
  14. Frontiers in microbiology · 2021
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Monica Losada-BarragánLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Adriana Umaña-PérezGrupo de Investigación en Hormonas, Departamento de Química, Universidad Nacional de Colombia, Bogotá, Colombia.
Jonathan DurãesLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Sergio Cuervo-EscobarFacultad de Ciencias, Universidad de Ciencias Aplicadas y Ambientales, Bogotá, Colombia.
Andrés Rodríguez-VegaLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Flávia L Ribeiro-GomesLaboratório de Pesquisa em Malária, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Luiz R BerbertLaboratório de Pesquisas sobre o Timo, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Fernanda MorgadoLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Renato PorrozziLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Daniella Arêas Mendes-da-CruzLaboratório de Pesquisas sobre o Timo, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Priscila AquinoInstituto Leônidas e Maria Deane, Fiocruz, Manaus, Brazil.
Paulo C CarvalhoComputational Mass Spectrometry and Proteomics Group, Fiocruz, Rio de Janeiro, Brazil.
Wilson SavinoLaboratório de Pesquisas sobre o Timo, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Myriam Sánchez-GómezGrupo de Investigación en Hormonas, Departamento de Química, Universidad Nacional de Colombia, Bogotá, Colombia.
Gabriel PadrónLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Patricia CuervoLaboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Fundação Oswaldo Cruz · BRUniversidad Nacional de Colombia · COInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular · BRUniversidad Antonio Nariño · COUniversity of Applied and Environmental Sciences · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detrimental effects of malnutrition on immune responses to pathogens have long been recognized and it is considered a main risk factor for various infectious diseases, including visceral leishmaniasis (VL). Thymus is a target of both malnutrition and infection, but its role in the immune response to

Indexed as

AnimalsBiological TransportCell MovementCell ProliferationCitric Acid CycleExosomesExtracellular FluidGalectin 1Gene Expression RegulationHost-Pathogen InteractionsImmunity, InnateLeishmania infantumLeishmaniasis, VisceralLipid MetabolismMaleMalnutritionGalectin 1Lgals1 protein, mousePlasminogenProteomefatty acid oxidationinterstitial fluidLeishmania infantumprotein malnutritionproteomicsthymic microenvironmentthymusvisceral leishmaniasis

Identifiers

PMID31355153
PMCPMC6639785
OpenAlexW2959516249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.