Evidence map›Paper›PMID 31355152›Full record

ArticleFrontiers in cellular and infection microbiology2019

Development, Optimization, and Validation of a High Throughput Screening Assay for Identification of Tat and Type II Secretion Inhibitors of

Francesco Massai, Michael Saleeb, Tugrul Doruk, Mikael Elofsson, Åke Forsberg

Open access · goldAbstract readValidation Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Anti-infective compounds forSustainable microbiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Metallacarborane Derivatives Effective againstInternational journal of molecular sciences · 2021
    Article
  7. Review
  8. Article
  9. Review of PotentialJournal of fungi (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francesco MassaiLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå University, Umeå, Sweden.
Michael SaleebDepartment of Chemistry, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Tugrul DorukLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå University, Umeå, Sweden.
Mikael ElofssonDepartment of Chemistry, Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
Åke ForsbergLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå University, Umeå, Sweden.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are becoming less effective in treatment of infections caused by multidrug-resistant

Indexed as

High-Throughput Screening AssaysAnti-Bacterial AgentsDose-Response Relationship, DrugDrug DiscoveryDrug Resistance, Multiple, BacterialProtein TransportPseudomonas aeruginosaSmall Molecule LibrariesTwin-Arginine-Translocation SystemType C PhospholipasesType II Secretion SystemsAnti-Bacterial AgentsSmall Molecule LibrariesTwin-Arginine-Translocation SystemType C PhospholipasesType II Secretion Systemshigh-throughput screeningphospholipase CPseudomonas aeruginosatwin arginine translocasetype II secretionvirulence inhibitors

Identifiers

PMID31355152
PMCPMC6635566
OpenAlexW2960259326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.