Evidence map›Paper›PMID 31355112›Full record

Article3 Biotech2019

Natural compounds from plants controlling leishmanial growth via DNA damage and inhibiting trypanothione reductase and trypanothione synthetase: an in vitro and in silico approach.

Shaila Mehwish, Huma Khan, Ashfaq Ur Rehman, Asif Ullah Khan, Mubarak Ali Khan, Obaid Hayat, Mansoor Ahmad, Abdul Wadood, Nazif Ullah

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. TargetingFrontiers in pharmacology · 2024
    Article
  3. Review
  4. EXCLI journal · 2024
    Article
  5. HAS 1: A natural product from soil-isolatedFrontiers in pharmacology · 2022
    Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shaila Mehwish1Department of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Huma Khan2Department of Biochemistry, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Ashfaq Ur Rehman2Department of Biochemistry, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Asif Ullah Khan2Department of Biochemistry, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Mubarak Ali Khan1Department of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Obaid Hayat1Department of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Mansoor Ahmad1Department of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Abdul Wadood2Department of Biochemistry, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Nazif Ullah1Department of Biotechnology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan, Mardan, Pakistan.ORCID 0000-0002-4564-5799
Abdul Wali Khan University Mardan · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, four different natural compounds including quercetin, gallic acid, rutin, and lupeol were studied for their anti-leishmanial potentials with anticipated mechanism of action through in vitro and in silico approaches. Results showed that rutin was exceedingly active (IC

Indexed as

Gallic acidLeishmaniasisLupeolQuercetinRutinTrypanothione reductaseTrypanothione synthetase

Identifiers

PMID31355112
PMCPMC6650509
OpenAlexW2963791976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.