Evidence map›Paper›PMID 31354976›Full record

SynthesisBMJ global health2019

Interventions to improve water supply and quality, sanitation and handwashing facilities in healthcare facilities, and their effect on healthcare-associated infections in low-income and middle-income countries: a systematic review and supplementary scoping review.

Julie Watson, Lauren D'Mello-Guyett, Erin Flynn, Jane Falconer, Joanna Esteves-Mills, Alain Prual, Paul Hunter, Benedetta Allegranzi, Maggie Montgomery, Oliver Cumming

Open access · goldAbstract readSystematic ReviewScoping Review
In one paragraph

Synthesis in BMJ global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 11 countries.

Julie WatsonDisease Control, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, UK.ORCID 0000-0003-1487-2443
Lauren D'Mello-GuyettDisease Control, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, UK.
Erin FlynnInfection and Immunity, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Jane FalconerLibrary and Archives Service, London School of Hygiene and Tropical Medicine, London, UK.
Joanna Esteves-MillsDisease Control, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, UK.
Alain PrualRegional Office for Western and Central Africa, UNICEF, Dakar, Senegal.
Paul HunterSchool of Medicine Health Policy and Practice, University of East Anglia, Norwich, UK.
Benedetta AllegranziGlobal Infection Prevention and Control Unit, World Health Organization, Geneva, Switzerland.
Maggie MontgomeryWater, Sanitation, Hygiene and Health, World Health Organization, Geneva, Switzerland.
Oliver CummingDisease Control, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, UK.
London School of Hygiene & Tropical Medicine · GBWorld Health Organization - Pakistan · PKLibrary and Archives Canada · CASouth Australian Health and Medical Research Institute · AUUniversity of East Anglia · GBWest and Central African Council for Agricultural Research and Development · SN

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionHealthcare-associated infections (HCAIs) are the most frequent adverse event compromising patient safety globally. Patients in healthcare facilities (HCFs) in low-income and middle-income countries (LMICs) are most at risk. Although water, sanitation and hygiene (WASH) interventions are likely important for the prevention of HCAIs, there have been no systematic reviews to date.

methodsAs per our prepublished protocol, we systematically searched academic databases, trial registers, WHO databases, grey literature resources and conference abstracts to identify studies assessing the impact of HCF WASH services and practices on HCAIs in LMICs. In parallel, we undertook a supplementary scoping review including less rigorous study designs to develop a conceptual framework for how WASH can impact HCAIs and to identify key literature gaps.

resultsOnly three studies were included in the systematic review. All assessed hygiene interventions and included: a cluster-randomised controlled trial, a cohort study, and a matched case-control study. All reported a reduction in HCAIs, but all were considered at medium-high risk of bias. The additional 27 before-after studies included in our scoping review all focused on hygiene interventions, none assessed improvements to water quantity, quality or sanitation facilities. 26 of the studies reported a reduction in at least one HCAI. Our scoping review identified multiple mechanisms by which WASH can influence HCAI and highlighted a number of important research gaps.

conclusionsAlthough there is a dearth of evidence for the effect of WASH in HCFs, the studies of hygiene interventions were consistently protective against HCAIs in LMICs. Additional and higher quality research is urgently needed to fill this gap to understand how WASH services in HCFs can support broader efforts to reduce HCAIs in LMICs. PROSPERO REGISTRATION NUMBER: CRD42017080943.

Indexed as

health education and promotionhygieneprevention strategiespublic healthsystematic review

Identifiers

PMID31354976
PMCPMC6626521
OpenAlexW2961462897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.