ReviewOpen heart
'Big issues' in neurodevelopment for children and adults with congenital heart disease.
Review in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- The association of neurodevelopmental abnormalities, congenital heart and renal defects in a tuberous sclerosis complex patient cohort.BMC medicine · 2022Pooled it
- Neurological Development in Very Low Birth Weight Infants with Congenital Heart Disease at 3 Years of Age: A Japanese Multicenter Study.Pediatric cardiology · 2026Article
- Corpus callosum and subarachnoid space measurements in fetuses with congenital heart disease: a prospective case-control study.Ultrasonography (Seoul, Korea) · 2026Article
- Online Information About Cardiac Neurodevelopment: Mixed Methods Study.JMIR pediatrics and parenting · 2026Article
- Early Neurodevelopmental Outcomes in Children With Congenital Heart Disease.JAMA network open · 2026Article
- A simulation study of a long-term neurodevelopmental care pathway for children with congenital heart disease.Pediatric research · 2026Article
- Spectral EEG in Congenital Heart Disease: A Case-Control Study in Infants Undergoing Cardiac Surgery.Pediatric cardiology · 2026Article
- Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease.Communications medicine · 2026Article
- Association between the gut microbiome and neurodevelopmental outcomes in infants with congenital heart disease: A prospective cohort study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Prioritizing Neurocognitive and Psychosocial Outcomes in Adults With Congenital Heart Disease: A Consensus Statement From the Adults With Congenital Heart Disease/Neuro 2024 Conference.Journal of the American Heart Association · 2026Article
- Medical & Socioeconomic Risk Factors Associated with Lack of Neurodevelopmental Evaluation Following Neonatal Cardiac Surgery.Pediatric cardiology · 2026Observational
- Disease and Economic Burden of Intellectual Developmental Disability Attributable to Congenital Heart Disease, 1990-2021.Global heart · 2026Article
- Never enough: bridging the gap between evidence and facts in the neurodevelopmental assessment of congenital heart disease children.Pediatric research · 2026Article
- Prevalence and Predictors of Neurocognitive Dysfunction in Adults With Congenital Heart Disease: Results From MINDS-ACHD.Journal of the American College of Cardiology · 2025Article
- Mental Health Care for Children with Heart Disease and Their Families: Practical Approaches and Considerations for the Pediatric and Pediatric Cardiology Clinician.Pediatric cardiology · 2025Review
- Cognitive Outcomes and Delirium After Cardiac Neurodevelopmental Program Implementation for Children With Congenital Heart Disease.JAMA network open · 2025Article
- Ras, RhoA, and vascular pharmacology in neurodevelopment and aging.Neurochemistry international · 2024Review
- Advance Care Planning for Adults With Moderate-to-Severe Congenital Heart Disease: Readiness Trial.CJC pediatric and congenital heart disease · 2024Article
- Validation of a Paralimbic-Related Subcortical Brain Dysmaturation MRI Score in Infants with Congenital Heart Disease.Journal of clinical medicine · 2024Article
- A case report of spastic diplegic cerebral palsy in a late preterm child with hypoplastic left heart syndrome.Translational pediatrics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is established that neurodevelopmental disability (NDD) is common in neonates undergoing complex surgery for congenital heart disease (CHD); however, the trajectory of disability over the lifetime of individuals with CHD is unknown. Several 'big issues' remain undetermined and further research is needed in order to optimise patient care and service delivery, to assess the efficacy of intervention strategies and to promote best outcomes in individuals of all ages with CHD. This review article discusses 'gaps' in our knowledge of NDD in CHD and proposes future directions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.