ArticleInternational journal of microbiology2019
Efficacy of Routine Fecal Microbiota Transplantation for Treatment of Recurrent
Article in International journal of microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Fecal Microbiota Transplantation and Microbiota-Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions.Clinical pharmacology and therapeutics · 2026Review
- Impact of Clostridioides difficile Infection on Clinical Outcomes in Hospitalized IBD Patients and the Role of Fecal Microbiota Transplantation: A Retrospective Cohort Study.The Kaohsiung journal of medical sciences · 2025Article
- Case report of clostridium difficile infection after rectal resection with ileostomy.World journal of surgical oncology · 2025Article
- The Role of Fecal Microbiota Transplantation (FMT) in the Management of Metabolic Diseases in Humans: A Narrative Review.Biomedicines · 2024Review
- Comparative Efficacy of Fecal Microbiota Transplantation in Treating Refractory or RecurrentBiomedicines · 2024Article
- Gut Microbiota-Gut Metabolites andMetabolites · 2024Review
- Safety and efficacy of fecal microbiota transplantation (FMT) as a modern adjuvant therapy in various diseases and disorders: a comprehensive literature review.Frontiers in immunology · 2024Review
- Pathogenicity and virulence ofVirulence · 2023Review
- Article
- Fecal Microbiota Transplant in Recurrent Clostridium Difficile Infections: A Systematic Review.Cureus · 2022Review
- Fecal microbiota transplantation and Clostridioides difficile infection among privately insured patients in the United States.Journal of gastroenterology · 2022Article
- The Multifunctional Sactipeptide Ruminococcin C1 Displays Potent Antibacterial Activity In Vivo as Well as Other Beneficial Properties for Human Health.International journal of molecular sciences · 2021Article
- Effect of Fiber and Fecal Microbiota Transplantation Donor on Recipient Mice Gut Microbiota.Frontiers in microbiology · 2021Article
- Autologous fecal transplantation from a lean state potentiates caloric restriction effects on body weight and adiposity in obese mice.Scientific reports · 2020Article
- Review
- Insights into the Role of Human Gut Microbiota inMicroorganisms · 2020Review
- Targeting Microbiota: What Do We Know about It at Present?Medicina (Kaunas, Lithuania) · 2019Review
- Pathobionts: mechanisms of survival, expansion, and interaction with host with a focus onGut microbesArticle
- Adverse events of fecal microbiota transplantation: a meta-analysis of high-quality studies.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with recurrent
methodsMedical records of all patients with recurrent CDI treated with FMT during the period 2013-2017 were reviewed. We evaluated cure of CDI-related diarrhea without relapse 10 weeks after FMT.
results47 patients were included. One treatment cured 25 patients (53%), and more than one treatment cured 32 patients (68%). Treatment outcome did not vary significantly with treatment with fresh donor feces or frozen fecal culture, days of use of antibiotics or days of hospitalization prior to CDI, and renal function or time from the first CDI to therapy. Treatment failure was associated with a significantly lower Karnofsky performance status score (70 points vs 90,
conclusionFecal instillation, for the treatment of relapsing CDI, is a promising approach, with 68% success rate reported in this study. The success rate of FMT is high, regardless of multiple comorbidities, extended use of antibiotics, or long time hospitalization. Although generally FMT is performed with fresh donor feces, our data show that the usage of frozen fecal culture could be an effective treatment alternative in recurrent CDI.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.