Evidence map›Paper›PMID 31354783›Full record

ArticleFrontiers in genetics2019

Polygenic Risk Score for Alzheimer's Disease Is Associated With Ch4 Volume in Normal Subjects.

Tao Wang, Zhifa Han, Yu Yang, Rui Tian, Wenyang Zhou, Peng Ren, Pingping Wang, Jian Zong, Yang Hu, Qinghua Jiang

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Cluster Analysis of Cortical Amyloid Burden for Identifying Imaging-driven Subtypes in Mild Cognitive Impairment.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
  3. Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tao WangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Zhifa HanSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Yu YangInformation Department, Jiangsu Singch Pharmaceutical Co., Ltd., Lianyungang, China.
Rui TianSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Wenyang ZhouSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Peng RenSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Pingping WangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Jian ZongSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Yang HuSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.
Qinghua JiangSchool of Life Sciences and Technology, Harbin Institute of Technology, Harbin, China.

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
NATIONAL ALZHEIMERS COORDINATING CENTER (NACC)U01AG016976 · NIA · UNIVERSITY OF WASHINGTON · PI KUKULL, WALTER ANTHONY · 1999 to 2020
$72.8M
Alzheimer's Disease Genetics ConsortiumU01AG032984 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SCHELLENBERG, GERARD DAVID · 2009 to 2024
$60.4M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Collaborative GWAS of Dementia, AD and related MRI and Cognitive EndophenotypesR01AG033193 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SESHADRI, SUDHA · 2009 to 2016
$4.4M
AGES STUDY-THE REYKJAVIK STUDY OF HEALTHY AGING FOR THE NEW MILLENNIUM-26012100N01AG012100 · NIA · ICELANDIC HEART ASSOCIATION · 2002 to 2004
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NHLBI NIH HHS R01 HL105756NIA NIH HHS N01 AG012100NIA NIH HHS R01 AG033193NIA NIH HHS U01 AG016976NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG032984NIA NIH HHS U24 AG021886Wellcome Trust
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a common neurodegenerative disease.

Indexed as

Alzheimer’s diseaseAPOECh4 regionpolygenic risk scoresingle nucleotide polymorphisms

Identifiers

PMID31354783
PMCPMC6636399

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.