Evidence map›Paper›PMID 31354721›Full record

ReviewFrontiers in immunology2019

Immunoregulatory Interplay Between Arginine and Tryptophan Metabolism in Health and Disease.

Giada Mondanelli, Alberta Iacono, Massimo Allegrucci, Paolo Puccetti, Ursula Grohmann

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Polysaccharide fromFoods (Basel, Switzerland) · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Dendritic cell maturation in cancer.Nature reviews. Cancer · 2025
    Review
  14. Circadian metabolic adaptations to infections.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  15. Review
  16. Article
  17. Ru@UiO-66-NHBiosensors · 2024
    Article
  18. Cold and hot tumors: from molecular mechanisms to targeted therapy.Signal transduction and targeted therapy · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giada MondanelliDepartment of Experimental Medicine, University of Perugia, Perugia, Italy.
Alberta IaconoDepartment of Experimental Medicine, University of Perugia, Perugia, Italy.
Massimo AllegrucciDepartment of Experimental Medicine, University of Perugia, Perugia, Italy.
Paolo PuccettiDepartment of Experimental Medicine, University of Perugia, Perugia, Italy.
Ursula GrohmannDepartment of Experimental Medicine, University of Perugia, Perugia, Italy.
University of Perugia · IT

Funding

European Research Council
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArginineHumansImmunomodulationSignal TransductionTryptophanArginineTryptophan3 dioxygenase 1arginase 1autoimmunitydendritc cellsindoleamine 2neoplasiapolyamine

Identifiers

PMID31354721
PMCPMC6629926
OpenAlexW2959042472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.