Evidence map›Paper›PMID 31354657›Full record

ArticleFrontiers in microbiology2019

Mutagenesis Induced by Sub-Lethal Doses of Ciprofloxacin: Genotypic and Phenotypic Differences Between the

Letícia Busato Migliorini, Holger Brüggemann, Romario Oliveira de Sales, Paula Célia Mariko Koga, Andrea Vieira de Souza, Marines Dalla Valle Martino, Rodrigo S Galhardo, Patricia Severino

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The Role of the SOS Response in the Adaptation ofCurrent issues in molecular biology · 2026
    Review
  2. Article
  3. Review
  4. Progressive Sub-MIC Exposure ofAntibiotics (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in microbiology · 2022
    Review
  9. Sub-Inhibitory Antibiotic Exposure and Virulence inAntibiotics (Basel, Switzerland) · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Letícia Busato MiglioriniHospital Israelita Albert Einstein, Albert Einstein Research and Education Institute, São Paulo, Brazil.
Holger BrüggemannDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Romario Oliveira de SalesHospital Israelita Albert Einstein, Albert Einstein Research and Education Institute, São Paulo, Brazil.
Paula Célia Mariko KogaHospital Israelita Albert Einstein, Laboratorio Clinico, São Paulo, Brazil.
Andrea Vieira de SouzaHospital Israelita Albert Einstein, Albert Einstein Research and Education Institute, São Paulo, Brazil.
Marines Dalla Valle MartinoHospital Israelita Albert Einstein, Laboratorio Clinico, São Paulo, Brazil.
Rodrigo S GalhardoDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Patricia SeverinoHospital Israelita Albert Einstein, Albert Einstein Research and Education Institute, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial resistance is a severe threat to global public health. Exposure to sub-lethal concentrations has been considered a major driver of mutagenesis leading to antibiotic resistance in clinical settings. Ciprofloxacin is broadly used to treat infections caused by

Indexed as

bacterial resistanceciprofloxacininduced mutagenesisPseudomonas aeruginosaumuDC

Identifiers

PMID31354657
PMCPMC6636244

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.