ArticleFrontiers in psychology2019
rs2572431 Polymorphism on Chromosome 8 Is Associated With Individual Differences in Anxiety Related Coping Modes.
Article in Frontiers in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Coping With Anxiety: Brain Structural Correlates of Vigilance and Cognitive Avoidance.Frontiers in psychiatry · 2022Article
- Similarities and dissimilarities between psychiatric cluster disorders.Molecular psychiatry · 2021Article
- Anxiety-Related Coping Styles, Social Support, and Internet Use Disorder.Frontiers in psychiatry · 2019Article
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Authors and funding
4 authors.
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Abstract
objectiveThe role of genetic factors in the interplay between anxiety-related coping and personality has been the subject of interest in numerous previous studies. The current study focused on anxiety-related coping modes, namely repression versus sensitization (i.e., cognitive avoidance versus vigilance), and the single nucleotide polymorphism (SNP) rs2572431. An association between this SNP and anxiety-related personality traits has previously been shown in a genome wide association study, thus further investigation of the relationship between this SNP and anxiety-related coping seems warranted.
methodsIn the present study,
resultsParticipants homozygous for the T-allele in rs2572431 showed the highest vigilance scores in all scenarios tested. This is in line with findings from an earlier genome wide association study demonstrating that the T-allele is also associated with higher neuroticism scores.
conclusionThe current study yields evidence for the role of rs2572431 in the molecular genetic underpinnings of coping modes and, more broadly, for its connection with personality.
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