Evidence map›Paper›PMID 31354265›Full record

ArticleInternational journal of nanomedicine2019

Cholesterol-rich lipid-mediated nanoparticles boost of transfection efficiency, utilized for gene editing by CRISPR-Cas9.

Elaheh Sadat Hosseini, Maryam Nikkhah, Saman Hosseinkhani

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 52 citations in OpenAlex.

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  13. New approaches to moderate CRISPR-Cas9 activity: Addressing issues of cellular uptake and endosomal escape.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Barriers and Strategies of Cationic Liposomes for Cancer Gene Therapy.Molecular therapy. Methods & clinical development · 2020
    Review
  18. Review
  19. Anti-F1000Research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elaheh Sadat HosseiniDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Maryam NikkhahDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Saman HosseinkhaniDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Tarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene EditingCationsCell DeathCholesterolCRISPR-Associated Protein 9CRISPR-Cas SystemsElectrophoretic Mobility Shift AssayEndosomesFatty Acids, MonounsaturatedGreen Fluorescent ProteinsHEK293 CellsHumansLiposomesNanoparticlesParticle SizePhosphatidylethanolamines1,2-dielaidoylphosphatidylethanolamine1,2-dioleoyloxy-3-(trimethylammonium)propaneCationsCholesterolCRISPR-Associated Protein 9enhanced green fluorescent proteinFatty Acids, MonounsaturatedGreen Fluorescent ProteinsLiposomesPhosphatidylethanolaminespolyethylene glycol-cholesterolPolyethylene GlycolsQuaternary Ammonium CompoundsRNA, Guide, CRISPR-Cas SystemsCas9/sgRNA deliverycationic liposomescholesterol domainsPEGylation

Identifiers

PMID31354265
PMCPMC6579871
OpenAlexW2952249183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.