Evidence map›Paper›PMID 31354172›Full record

ArticleMacromolecules2019

Tuning H

Jeffrey C Foster, Ryan J Carrazzone, Nathan J Spear, Scott C Radzinski, Kyle J Arrington, John B Matson

Open access · greenAbstract read
In one paragraph

Article in Macromolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Linking homocysteine and ferroptosis in cardiovascular disease: insights and implications.Apoptosis : an international journal on programmed cell death · 2024
    Review
  4. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Linker-Regulated HBiomacromolecules · 2020
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeffrey C FosterDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.ORCID 0000-0002-9097-8680
Ryan J CarrazzoneDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.
Nathan J SpearDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.
Scott C RadzinskiDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.
Kyle J ArringtonDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.
John B MatsonDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.ORCID 0000-0001-7984-5396
Virginia Tech · US

Funding

Delivery of H2S: Supramolecular and Enzyme-Triggered Strategies for Controlled ReleaseR01GM123508 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MATSON, JOHN B · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM123508
6 · The paper itself

Abstract

Drug delivery from polymer micelles has been widely studied, but methods to precisely tune rates of drug release from micelles are limited. Here, the mobility of hydrophobic micelle cores was varied to tune the rate at which a covalently bound drug was released. This concept was applied to cysteine-triggered release of hydrogen sulfide (H

Identifiers

PMID31354172
PMCPMC6660018
OpenAlexW2912322270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.