Evidence map›Paper›PMID 31354029›Full record

ArticleEpigenetics

Human chromatin remodeler cofactor, RNA interactor, eraser and writer sperm RNAs responding to obesity.

Grace M Swanson, Molly Estill, Michael P Diamond, Richard S Legro, Christos Coutifaris, Kurt T Barnhart, Hao Huang, Karl R Hansen, J C Trussell, R Matthew Coward and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Grace M SwansonDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, USA.
Molly EstillDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, USA.
Michael P DiamondDepartment of Obstetrics and Gynecology, Augusta University, Augusta, USA.
Richard S LegroDepartment of Obstetrics and Gynecology, Pennsylvania State University, Hershey, USA.
Christos CoutifarisDepartment of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, USA.
Kurt T BarnhartDepartment of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, USA.
Hao HuangDepartment of Biostatistics, Yale University School of Public Health, New Haven, USA.
Karl R HansenDepartment of Obstetrics and Gynecology, University of Oklahoma College of Medicine, Oklahoma City, USA.
J C TrussellUrology Department, Upstate Medical University, Syracuse, USA.
R Matthew CowardDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, USA.
Heping ZhangDepartment of Biostatistics, Yale University School of Public Health, New Haven, USA.ORCID 0000-0002-0688-4076
Robert GoodrichDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, USA.
Stephen A KrawetzDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, USA.
Wayne State University · USUniversity of Pennsylvania · USYale University · USAugusta University · USPennsylvania State University · USSUNY Upstate Medical University · USUniversity of North Carolina at Chapel Hill · USUniversity of Oklahoma · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORKU10HD027049 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI COUTIFARIS, CHRISTOS · 1990 to 2017
$5.2M
GHSU/WSU Cooperative Reproductive Medicine NetworkU10HD039005 · NICHD · WAYNE STATE UNIVERSITY · PI DIAMOND, MICHAEL PETER · 2000 to 2017
$5.2M
Luteal Progesterone Supplementation in Clomiphene Citrate-IUI CyclesU10HD077680 · NICHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HANSEN, KARL RICHARD · 2013 to 2017
$1.5M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS U10 HD027049NICHD NIH HHS U10 HD039005NICHD NIH HHS U10 HD077680
6 · The paper itself

Abstract

In the United States almost 33% of adults are considered obese (BMI > 30 kg/m

Indexed as

TranscriptomeAdultBody Mass IndexChromatin Assembly and DisassemblyDNA MethylationGene Regulatory NetworksHumansMaleObesityRNA Processing, Post-TranscriptionalSpermatozoaBMICREWs - chromatin remodeler cofactor RNA interactor eraser and writer RNAsobesitysperm RNA

Identifiers

PMID31354029
PMCPMC6961666
OpenAlexW2966415185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.