Evidence map›Paper›PMID 31353393›Full record

ReviewThe international journal of neuropsychopharmacology2019

Opportunities in Novel Psychotropic Drug Design from Natural Compounds.

Siu Wa Tang, Wayne H Tang

Abstract readReview
In one paragraph

Review in The international journal of neuropsychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Frontiers in psychiatry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Siu Wa TangDepartment of Psychiatry, University of California, Irvine, California; North Campus Psychiatry Trailer, Irvine, California.
Wayne H TangDepartment of Psychiatry, University of California, Irvine, California; North Campus Psychiatry Trailer, Irvine, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple initiatives at the national and international level support natural drug discovery. Psychiatrists and patients are not well informed about natural psychotropics in general. Existing antidepressant and antipsychotic drugs were developed from atropine, a natural product. Subsequent drug developments were largely based on extension and modification of earlier molecular scaffolds. This limits their mechanisms of action to similar neuropathways. Natural psychotropic substances, particularly those with hallucinogenic and psychedelic properties and different chemical structures, may serve as new paths to novel psychotropic drug development.

Indexed as

Drug DesignBiological ProductsDrug DevelopmentHumansPhytochemicalsPsychotropic DrugsBiological ProductsPhytochemicalsPsychotropic Drugsbotanical psychotropicsdesigner drugsnatural psychoactive substancespsychotropic designs

Identifiers

PMID31353393
PMCPMC6754733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.