Evidence map›Paper›PMID 31353163›Full record

ArticleAmerican journal of preventive medicine2019

The Impact of Following Solid Food Feeding Guides on BMI Among Infants: A Simulation Study.

Marie C Ferguson, Kelly J O'Shea, Lawrence D Hammer, Daniel L Hertenstein, Nathaniel J Schwartz, Lucas E Winch, Sheryl S Siegmund, Bruce Y Lee

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marie C FergusonGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Kelly J O'SheaGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Lawrence D HammerDepartment of Pediatrics, Stanford University, Stanford, California.
Daniel L HertensteinGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Nathaniel J SchwartzGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Lucas E WinchGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Sheryl S SiegmundGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland.
Bruce Y LeeGlobal Obesity Prevention Center (GOPC) at Johns Hopkins, Baltimore, Maryland; Public Health Computational and Operations Research (PHICOR), Baltimore, Maryland. Electronic address: bruceleemdmba@gmail.com.

Funding

MULTILEVEL SYSTEMS-ORIENTED CHILDHOOD OBESITY STUDY IN CHINAU54HD070725 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CURRIERO, FRANK · 2011 to 2016
$15.9M
Early Life Determinants of Obesity in U.S. Urban Low Income Minority Birth CohortR01HD086013 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y, WANG, XIAOBIN · 2016 to 2020
$3.3M
Virtual Population Obesity Prevention (VPOP) Labs: Computational, Multi-Scale Models for Obesity SolutionsU01HD086861 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2015 to 2019
$2.8M
Regional Healthcare Ecosystem Analyst for Healthcare Associated InfectionsR01HS023317 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2014 to 2014
$2.4M
AHRQ HHS R01 HS023317NICHD NIH HHS R01 HD086013NICHD NIH HHS U01 HD086861NICHD NIH HHS U54 HD070725
6 · The paper itself

Abstract

introductionThere are several recommendations advising caregivers when and how to introduce solid food to infants. These complementary feeding guides vary in terms of the recommendations for timing and portions. The objective of this study is to determine the impact of following different guidelines on weight trajectories of infants.

methodsIn 2018, the study team developed a computational simulation model to capture feeding behaviors, activity levels, metabolism, and body size of infants from 6 months to 1 year. Daily food intake of virtual infants based on feeding recommendations translated to changes in body weight. Next, simulations tested the impact of the following complementary feeding recommendations that provided amount, type, and timing of foods: Children's Hospital of Philadelphia, Johns Hopkins Medicine, Enfamil, and Similac.

resultsWhen virtual caregivers fed infants according to the four different guides, none of the simulated situations resulted in normal weight at 12 months when infants were also being breastfed along average observed patterns. Reducing breast milk portions in half while caregivers fed infants according to complementary feeding guidelines resulted in overweight BMIs between 9 and 11 months for Children's Hospital of Philadelphia, Johns Hopkins Medicine, and Enfamil guidelines. Cutting breast milk portions in half also led to infants reaching unhealthy underweight BMI percentiles between 7 and 11 months for female and male infants when caregivers followed Children's Hospital of Philadelphia, Johns Hopkins Medicine, and Similac guidelines.

conclusionsThis study identified situations in which infants could reach unhealthy weights, even while following complementary feeding guidelines, suggesting that current recommended portion sizes should be tightened.

Indexed as

Body Mass IndexModels, BiologicalBody WeightBreast FeedingComputer SimulationExerciseFeeding BehaviorFemaleGuidelines as TopicHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaMaleOverweightPhiladelphia

Identifiers

PMID31353163
PMCPMC6871772

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.