Evidence map›Paper›PMID 31353159›Full record

ArticleThe American journal of emergency medicine2020

Hepatitis B screening in an argentine ED: Increasing vaccination in a resource-limited setting.

James S Ford, Leonardo G Marianelli, Natalia Frassone, Jose D Debes

Abstract read
In one paragraph

Article in The American journal of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James S FordDepartment of Emergency Medicine, University of California Davis School of Medicine, Sacramento, CA, USA.
Leonardo G MarianelliDepartment of Infectious Diseases, Hospital Rawson, Cordoba, Cordoba, Argentina.
Natalia FrassoneDepartment of Infectious Diseases, Hospital Rawson, Cordoba, Cordoba, Argentina.
Jose D DebesDepartment of Medicine, University of Minnesota, Minneapolis, MN, USA. Electronic address: debes003@umn.edu.

Funding

Assessment of gene expression profiles related to hepatocellular carcinoma in HCV: singlecell hepatocyte sequencing as a tool to identify cancer-related genesR21CA215883 · NCI · UNIVERSITY OF MINNESOTA · PI DEBES, JOSE DANIEL · 2018 to 2019
$362k
NCI NIH HHS R21 CA215883
6 · The paper itself

Abstract

backgroundThere is limited data regarding the use of emergency departments (EDs) for infectious disease screening and vaccination in resource-limited regions. In these settings, EDs are often the only contact that patients have with the healthcare system, turning an ED visit into an opportune time to deliver preventative health services.

methodsIn this pilot study, patients that met inclusion criteria were prospectively tested for hepatitis B surface antigen test (HBsAg). Previously unvaccinated patients who tested negative for HBsAg were offered HBV vaccination. The study setting was a public infectious disease hospital in Cordoba, Argentina. The primary outcomes were new HBV diagnoses, as well as vaccination completion between screening modalities (Point-of-Care-Testing-POCT vs. laboratory testing) and same vs. different day vaccination.

resultsWe screened 100 patients for HBV (75 POCT & 25 laboratory). The median age of participants was 35 years (IQR 24-52) and 55% were male. No patients tested positive for HBsAg. All patients who completed first dose vaccination were initially screened with the POCT. No patients screened with laboratory testing returned for vaccination. Patients who were scheduled for vaccination the same day were more likely to complete vaccination compared to those scheduled for another day (75% vs. 14%, p < .001).

conclusionOur study supports the use of HBV POCTs in the ED in conjunction with vaccination of HBV-negative individuals. In regions with low HBV endemicity, direct vaccination without HBsAg testing may be more cost effective. We believe that this acute-care screening model is applicable to other resource-limited settings.

Indexed as

Emergency Service, HospitalAdultArgentinaFemaleHepatitis BHepatitis B Surface AntigensHepatitis B VaccinesHumansMaleMass ScreeningMiddle AgedPilot ProjectsPoint-of-Care TestingProspective StudiesSerologic TestsVaccinationHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B vaccinationHepatitis B virusPoint-of-care testRapid diagnostic test

Identifiers

PMID31353159
PMCPMC6980425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.