Evidence map›Paper›PMID 31352654›Full record

ArticleInternal and emergency medicine2020

Procalcitonin in hemodialysis patients presenting with fever or chills to the emergency department.

R Schneider, M J Cohen, S Benenson, O Duchin, Y S Haviv, M Elhalel-Darnitski, P D Levin

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

R SchneiderDivision of Internal Medicine, Nephrology Service, Ein Kerem campus, 91120, Jerusalem, Israel.
M J CohenDepartment of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Ein Kerem campus, POB 12000, 91120, Jerusalem, Israel.
S BenensonDepartment of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Ein Kerem campus, POB 12000, 91120, Jerusalem, Israel. Benenson@hadassah.org.il.
O DuchinDivision of Internal Medicine, Nephrology Service, Ein Kerem campus, 91120, Jerusalem, Israel.
Y S HavivNephrology Department, Soroka Medical Center, Rager Boulevard, 85025, Beer Sheva, Israel.
M Elhalel-DarnitskiDivision of Internal Medicine, Nephrology Service, Ein Kerem campus, 91120, Jerusalem, Israel.
P D LevinIntensive Care Unit Shaare-Zedek Medical Center, Shmuel Bait St., 9103102, Jerusalem, Israel.
Hadassah Medical Center · ILShaare Zedek Medical Center · ILSoroka Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to assess the role of procalcitonin in discriminating severe bacterial infections requiring antibiotic treatment from non-bacterial causes of fever or chills in chronic dialysis patients. Chronic hemodialysis patients who were admitted to the emergency room due to fever and/or chills were recruited to the study. The presence or absence of bacterial infection was defined after recruitment conclusion by an infectious disease specialist who was blinded to procalcitonin results. Procalcitonin levels were compared between infected and non-infected patients. Out of 54 patients recruited, 22 (41%) patients eventually diagnosed with infection. Mean (± SD) procalcitonin values were 4.3 (± 5.5) ng/ml among cases, 1.0 (± 2.0) ng/ml among controls with no infection (p = 0.02). A cutoff PCT value of 1 ng/ml or higher had 77% sensitivity and 59% specificity for the diagnosis of severe infection. Procalcitonin cannot usefully identify hemodialysis patient with bacterial infection.

Indexed as

AgedAged, 80 and overArea Under CurveBacteremiaBiomarkersChillsEmergency Service, HospitalFemaleFeverHumansMaleMiddle AgedProcalcitoninRenal DialysisROC CurveBiomarkersProcalcitoninBacterial infectionHemodialysisProcalcitonin

Identifiers

PMID31352654
OpenAlexW2966777387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.