Evidence map›Paper›PMID 31352624›Full record

ReviewHeart failure reviews2020

Prevention of non-response to cardiac resynchronization therapy: points to remember.

Huolan Zhu, Tong Zou, You Zhong, Chenguang Yang, Yirong Ren, Fang Wang

Open access · hybridAbstract readReview
In one paragraph

Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Echocardiography- versus intracardiac electrocardiogram-based optimization of cardiac resynchronization therapy: A systematic review.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Pooled it
  3. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huolan ZhuDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China.ORCID 0000-0002-9845-4494
Tong ZouDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China.
You ZhongDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China.
Chenguang YangDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China.
Yirong RenDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China.
Fang WangDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Dahua Road No.1, Beijing, 100730, People's Republic of China. 294216621@qq.com.
Beijing Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) is an important and effective therapy for end-stage heart failure. Non-response to CRT is one of the main obstacles to its application in clinical practice. There is no uniform consensus or definition of CRT "response." Clinical symptoms, ventricular remodeling indices, and cardiovascular events have been reported to be associated with non-responders. To prevent non-response to CRT, three aspects should be thoroughly considered: preoperative patient selection, electrode implantation, and postoperative management. Preoperative selection of appropriate patients for CRT treatment is an important step in preventing non-response. Currently, the CRT inclusion criteria are mainly based on the morphology of QRS waves in deciding ventricular dyssynchrony. Echocardiography and cardiac magnetic resonance are being explored to predict nonresponse to CRT. The location of left ventricular electrode implantation is a current hot spot of research; it is important to identify the location of the latest exciting ventricular segment and avoid scars. Cardiac magnetic resonance and ultrasonic spot tracking are being progressively developed in this field. Some new techniques such as His Bundle pacing, endocardial electrodes, and novel sensors are also being investigated. Postoperative management of patients is another essential step towards preventing non-response; it mainly focuses on the treatment of the disease itself and CRT program control optimization. CRT treatment is just one part of the overall treatment of heart failure, and multidisciplinary efforts are needed to improve the overall outcome.

Indexed as

Cardiac Resynchronization TherapyEchocardiographyHeart FailureHeart VentriclesHumansTreatment OutcomeVentricular Function, LeftVentricular RemodelingCardiac synchronizationElectrode implantationNon-responsePatient selectionProgram control optimization

Identifiers

PMID31352624
PMCPMC7046599
OpenAlexW2964974543

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.