Trial reportEnvironmental science and pollution research international2019
Canned food intake and urinary bisphenol a concentrations: a randomized crossover intervention study.
Trial report in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05780047 (Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (EDCs) in Women of Child-Bearing Age and Their Partners
Who cites it
20 citing papers in PubMed.
- Low-plastic diet and urinary levels of plastic-associated phthalates and bisphenols: the randomized controlled PERTH Trial.Nature medicine · 2026Trial
- Can exposure to chemical products be reduced during pregnancy?BMC pregnancy and childbirth · 2026Trial
- Urinary bisphenol levels and blood pressure after soda consumption from cans, PET and glass bottles.Scientific reports · 2025Trial
- Perinatal Environmental Health Education Intervention to Reduce Exposure to Endocrine Disruptors: The PREVED Project.International journal of environmental research and public health · 2021Trial
- Comparison of the Effects of Plastic-Free Diet, Plastic-Free Diet Education and Exposure Feedback on Urinary Bisphenol: A Levels in Adolescents.The Journal of school nursing : the official publication of the National Association of School Nurses · 2026Article
- Bisphenol A and prostate cancer: from population exposure to context-dependent mechanisms and translational implications.Frontiers in cell and developmental biology · 2026Review
- Endocrine Disruptors in Child Obesity and Related Disorders: Early Critical Windows of Exposure.Current nutrition reports · 2025Review
- Hair care product use among pregnant women of color: protocol for a feasibility educational intervention.Frontiers in reproductive health · 2025Article
- Navigating Cardiovascular Challenges of Obesity: Exploring Preventive Approaches.Endocrine, metabolic & immune disorders drug targets · 2025Review
- Article
- Recent use of consumer and personal care products and exposures to select endocrine disrupting chemicals among urban children with asthma.Journal of exposure science & environmental epidemiology · 2024Article
- Bisphenol A-What Do We Know? A Global or Local Approach at the Public Health Risk Level.International journal of molecular sciences · 2024Review
- Effects of Behavioral, Clinical, and Policy Interventions in Reducing Human Exposure to Bisphenols and Phthalates: A Scoping Review.Environmental health perspectives · 2024Article
- Risk assessment of food contact materials.EFSA journal. European Food Safety Authority · 2023Article
- Interventions to Reduce Exposure to Synthetic Phenols and Phthalates from Dietary Intake and Personal Care Products: a Scoping Review.Current environmental health reports · 2023Article
- Lifestyle interventions to reduce endocrine-disrupting phthalate and phenol exposures among reproductive age men and women: A review and future steps.Environment international · 2022Review
- Interventions on Reducing Exposure to Endocrine Disrupting Chemicals in Human Health Care Context: A Scoping Review.Risk management and healthcare policy · 2022Article
- Ultra-processed Foods and Cardiovascular Diseases: Potential Mechanisms of Action.Advances in nutrition (Bethesda, Md.) · 2021Review
- Effects of a dietary modification intervention on menstrual pain and urinary BPA levels: a single group clinical trial.BMC women's health · 2021Article
- Cross Sectional Study on Exposure to BPA and Phthalates and Semen Parameters in Men Attending a Fertility Center.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Bisphenol A (BPA) is an endocrine disruptor. To evaluate the effect of canned food consumption on internal BPA dose, urinary BPA concentrations were measured before and after intake of canned foods. This study applied a randomized crossover design, recruited 20 healthy volunteers, and divided them into two groups. One group consumed canned food; the other group consumed fresh food. After a 1-day washout, the dietary interventions were reversed. In each period, urine samples were collected immediately before meals and then 2 h, 4 h, and 6 h after meals. A mixed-effects model was used to assess BPA changes over time. Our results showed urinary BPA concentrations increased after consumption of canned food. Specifically, urinary BPA concentrations significantly differed between consumption of canned food and fresh food at 2 h, 4 h, and 6 h after intake (p values of 0.001, < 0.001, and < 0.001, respectively). Mean BPA concentrations at 2 h, 4 h, and 6 h after meals were 152%, 206%, and 79% higher, respectively, than mean BPA concentrations before meals. Urine concentration profiles of canned food intake showed that peaks were at 4 h, the increase diminished at 6 h, and returned to baseline levels at 24 h after intake. Therefore, dietary intervention and a 1-day washout period are effective for limiting internal BPA burden. This study provides convincing evidence of a human exposure route to BPA and a basis for designing interventions to mitigate exposure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.