ArticleBMJ open2019
Clinical and epidemiological indicators and spatial analysis of leprosy cases in patients under 15 years old in an endemic area of Northeast Brazil: an ecological and time series study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Access and utilisation of leprosy healthcare services in high-burden districts in Ethiopia.Southern African journal of infectious diseases · 2024Article
- Reduced HIV/AIDS diagnosis rates and increased AIDS mortality due to late diagnosis in Brazil during the COVID-19 pandemic.Scientific reports · 2023Article
- Leprosy among new child cases in China: Epidemiological and clinical analysis from 2011 to 2020.PLoS neglected tropical diseases · 2023Article
- sTREM-1 and TNF-α levels are associated with the clinical outcome of leprosy patients.Frontiers in medicine · 2023Article
- Impact of the COVID-19 pandemic on the diagnosis of leprosy in Brazil: An ecological and population-based study.Lancet regional health. Americas · 2022Article
- Spatio-temporal analysis of leprosy risks in a municipality in the state of Mato Grosso-Brazilian Amazon: results from the leprosy post-exposure prophylaxis program in Brazil.Infectious diseases of poverty · 2022Article
- Spatiotemporal Pattern of COVID-19-Related Mortality during the First Year of the Pandemic in Brazil: A Population-based Study in a Region of High Social Vulnerability.The American journal of tropical medicine and hygiene · 2021Article
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Authors and funding
12 authors.
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Abstract
objectiveThis study aimed to analyse the clinical and epidemiological indicators, temporal trends and the spatial distribution of leprosy in patients under 15 years old in an endemic area of Northeast Brazil.
designRegional surveillance study of all reported cases.
settingState of Sergipe, endemic area of Northeast Brazil.
methodsAn ecological and time series study was conducted, based on secondary data reported by the Brazilian Information System on Notifiable Diseases for leprosy cases diagnosed in Sergipe state (2002-2015). The analysis of temporal trends was performed using the Joinpoint Regression Programme through Poisson regression. We performed spatial analysis by Kernel estimator and Moran index.
resultsThe incidence rate was reduced from 6.29 to 3.78 cases per 100 000 inhabitants in 2002 and 2015, respectively. However, Sergipe was still classified as highly endemicity in 2015. The mean number of household contacts (HHC) examined was significantly lower than those registered. Clinical data indicated that 21.4% of the patients developed leprosy reactions, and 31.3% presented with some physical disability in the multibacillary groups. Patients diagnosed by examination within the HHC presented better indicators, such as lower percentage of leprosy reaction and physical disability. Spatial analysis showed the most risk areas distributed on the northeast and cities around the capital, Aracaju.
conclusionThe data indicate that there is a persistence of active
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