Evidence map›Paper›PMID 31352308›Full record

Trial reportDrug and alcohol dependence2019

Methamphetamine use drives decreases in viral suppression for people living with HIV released from a large municipal jail: Results of the LINK LA clinical trial.

David Goodman-Meza, Steve Shoptaw, Robert E Weiss, Terry Nakazono, Nina T Harawa, Sae Takada, Wendy H Garland, William E Cunningham

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Integrating HIV and Stimulant-Use Disorder Treatment: A Pilot Implementation Effectiveness Trial of Contingency Management in HIV Care.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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  8. Review
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  12. Overamped: Stimulant Use and HIV Pathogenesis.Current HIV/AIDS reports · 2023
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David Goodman-MezaDivision of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Steve ShoptawDepartment of Family Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Robert E WeissDepartment of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Terry NakazonoDepartment of Medicine, Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Nina T HarawaDepartment of Family Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Charles R. Drew University College of Medicine, Los Angeles, CA, USA.
Sae TakadaNational Clinician Scholars Program UCLA, Division of General Internal Medicine and Health Services Research, Department of Medicine, Los Angeles, CA, USA; VA HSR and D Center for the Study of Healthcare Innovation, Implementation, and Policy, Los Angeles, CA, USA.
Wendy H GarlandDivision of HIV and STD Programs, Los Angeles County Department of Public Health, Los Angeles, CA, USA.
William E CunninghamDepartment of Medicine, Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Department of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · USCenter for the Study of Healthcare Provider Behavior · USLos Angeles County Department of Public Health · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZACK, JEROME A. · 1991 to 2018
$39.9M
The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Homero Erwin del Pino · 2002 to 2026
$19.7M
NRSA Training CoreTL1TR001883 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI, Nina Thawata Harawa · 2016 to 2026
$8.6M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
Effectiveness of Peer Navigation to Link Released HIV+ Jail Inmates to HIV CareR01DA030781 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CUNNINGHAM, WILLIAM EMERY · 2010 to 2015
$4.5M
HIV intervention models for criminal justice involved substance-using Black MSMR01DA039934 · NIDA · UNIVERSITY OF CHICAGO · PI FUJIMOTO, KAYO, HARAWA, NINA THAWATA · 2015 to 2019
$3.6M
Youth Services Navigation Intervention for HIV+ adolescents and young adults being released from incarceration: A randomized control trialR01MD011773 · NIMHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BELZER, MARVIN E, HARAWA, NINA THAWATA · 2017 to 2021
$3.5M
A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African AmericansR01NR017334 · NINR · RAND CORPORATION · PI BOGART, LAURA M · 2017 to 2021
$3.1M
Effect of Peer Navigation and Contingency Management on Retention in HIV CareR01MH103076 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ETTNER, SUSAN LOUISE · 2014 to 2018
$2.8M
NCATS NIH HHS TL1 TR001883NCATS NIH HHS UL1 TR001881NIAID NIH HHS P30 AI028697NIA NIH HHS P30 AG021684NIDA NIH HHS R01 DA030781NIDA NIH HHS R01 DA039934NIMHD NIH HHS R01 MD011773NIMH NIH HHS P30 MH058107NIMH NIH HHS R01 MH103076NIMH NIH HHS T32 MH080634NINR NIH HHS R01 NR017334
6 · The paper itself

Abstract

backgroundPeople living with HIV (PLWH) often experience decreases in HIV viral suppression (VS) after release from jail. The Linking Inmates to Care in LA (LINK LA) peer navigation intervention helped maintain VS 12 months after release from jail compared to standard of care. In this study, we analyzed correlates of substance use and tested whether substance use was an independent correlate of decreased VS in LINK LA participants.

methodsWe analyzed LINK LA data collected at baseline, 3, and 12 months. We defined high-risk drug use as any reported methamphetamine, cocaine, or opioid use in the 30 days prior to a study visit (or jail entry at baseline). We used generalized linear mixed models to test associations of sociodemographic variables with type of substance used, and we tested correlates of VS while controlling for time, the intervention, and their interaction.

resultsAt baseline (n = 356), 71% of participants reported high-risk drug use: 58%, methamphetamine; 17%, cocaine; 7%, heroin; and 4%, prescription opioids. Non-Hispanic Whites and those younger than 35 were most likely to use methamphetamine; Blacks were most likely to use cocaine; people who inject drugs were most likely to use opioids. Participants who used high-risk drugs had 53% lower adjusted odds than non-users of maintaining VS (AOR 0.47, 95% CI 0.31-0.70, p < 0.001).

conclusionHigh-risk drug use, dominated by methamphetamine use, independently correlated with decreased VS among recently incarcerated PLWH. Improving HIV care continuum outcomes among populations leaving jail requires attention to efforts to address high-risk drug use.

Indexed as

AdultAnalgesics, OpioidAnti-HIV AgentsCocaineContinuity of Patient CareFemaleHIV InfectionsHumansLinear ModelsLos AngelesMaleMethamphetamineMiddle AgedPatient Acceptance of Health CarePrisonersPrisonsAnalgesics, OpioidAnti-HIV AgentsCocaineMethamphetamineHIV viral suppressionJailMethamphetamineStimulantSubstance use

Identifiers

PMID31352308
PMCPMC6686887
OpenAlexW2959120308

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.