ReviewCurrent opinion in psychology2019
Mindfulness meditation and gene expression: a hypothesis-generating framework.
Review in Current opinion in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training: findings from an exploratory randomised trial.Scientific reports · 2020Trial
- The role of mindfulness training supported by virtual reality in the nonpharmacological treatment of schizophrenia-research design.Annals of general psychiatry · 2025Article
- Parasympathetic nervous activity and CTRA gene expression among healthy young adults in Japan.Brain, behavior, & immunity - health · 2025Article
- Transcriptomics and psychotherapy: An integrative review.Brain, behavior, & immunity - health · 2024Review
- [A biobehavioral theoretical framework based on the mechanism of cellular aging for nursing interventions to promote autonomic balance].Journal of Korean biological nursing science · 2024Review
- Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease.Brain, behavior, & immunity - health · 2023Article
- Article
- Cellular signaling pathways as plastic, proto-cognitive systems: Implications for biomedicine.Patterns (New York, N.Y.) · 2023Review
- Effects of Mindfulness-Based Therapy on Clinical Symptoms and DNA Methylation in Patients with Polycystic Ovary Syndrome and High Metabolic Risk.Current issues in molecular biology · 2023Article
- Underlying mechanisms of mindfulness meditation: Genomics, circuits, and networks.World journal of psychiatry · 2022Review
- Changes in the expression of inflammatory and epigenetic-modulatory genes after an intensive meditation retreat.Comprehensive psychoneuroendocrinology · 2022Article
- Are sick people really more impulsive?: Investigating inflammation-driven impulsivity.Psychoneuroendocrinology · 2022Review
- Mindfulness interventions for offsetting health risk following early life stress: Promising directions.Brain, behavior, & immunity - health · 2021Article
- Cortical and autonomic responses during staged Taoist meditation: Two distinct meditation strategies.PloS one · 2021Article
- A Case Report of a Rapidly Growing Giant Pilomatrixoma on the Posterior Shoulder in a 12-Year-Old Male Patient.Skin appendage disorders · 2020Article
- The Potential Impact of Social Genomics on Wound Healing.Advances in wound care · 2020Review
- The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature.Frontiers in medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Recent research in functional genomics shows that social stressors affect the expression of immune response genes. These effects are mediated in part via our adaptive capacity for intracellular molecules to respond to extracellular signals, a process called signal transduction. Under this framework, one-way stressors can be transduced into cellular changes is through central nervous system (CNS) modulation of peripheral neural, endocrine, and molecular activity. Mindfulness meditation is a consciousness discipline used to cultivate attention and self-regulation, and may thus be relevant to the signal transduction process outlined in the social genomics literature. In this opinion article, we briefly review results from existing controlled trials that test the effects of mindfulness meditation on gene expression. We then speculate on a mind-body conceptual model, grounded in existing social genomics theory. In the spirit of hypothesis generation, we argue that mindfulness meditation changes brain activity patterns related to attention, self-regulation, and threat evaluation and so may alter the signal transduction process that regulates the expression of immune response genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.