Evidence map›Paper›PMID 31352218›Full record

ArticleNeuroImage. Clinical2019

Dopamine D2/D3 receptor abnormalities after traumatic brain injury and their relationship to post-traumatic depression.

Amy E Jolly, Vanessa Raymont, James H Cole, Alex Whittington, Gregory Scott, Sara De Simoni, Graham Searle, Roger N Gunn, David J Sharp

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Amy E JollyDivision of Brain Sciences, Department of Medicine, Imperial College London, UK. Electronic address: amy.jolly@imperial.ac.uk.
Vanessa RaymontDivision of Brain Sciences, Department of Medicine, Imperial College London, UK; Centre of Dementia Prevention, Centre for Clinical Brain Sciences, University of Edinburgh, UK; Department of Psychiatry, University of Oxford, UK. Electronic address: v.raymont@imperial.ac.uk.
James H ColeDivision of Brain Sciences, Department of Medicine, Imperial College London, UK. Electronic address: james.cole@imperial.ac.uk.
Alex WhittingtonInvicro, Centre for Imaging Sciences, Imperial College London, UK. Electronic address: a.whittington13@imperial.ac.uk.
Gregory ScottDivision of Brain Sciences, Department of Medicine, Imperial College London, UK. Electronic address: gregory.scott99@imperial.ac.uk.
Sara De SimoniDivision of Brain Sciences, Department of Medicine, Imperial College London, UK. Electronic address: s.desimoni@imperial.ac.uk.
Graham SearleInvicro, Centre for Imaging Sciences, Imperial College London, UK. Electronic address: graham.searle@invicro.co.uk.
Roger N GunnInvicro, Centre for Imaging Sciences, Imperial College London, UK. Electronic address: roger.gunn@imperial.ac.uk.
David J SharpDivision of Brain Sciences, Department of Medicine, Imperial College London, UK. Electronic address: david.sharp@imperial.ac.uk.
Imperial College London · GBInvicro (United Kingdom) · GB

Funding

Department of Health NIHR-RP-011-048
6 · The paper itself

Abstract

objectiveTo investigate dopamine D2/D3 receptor availability following traumatic brain injury (TBI) and their relationship to the presence of DSM-IV Major Depressive Disorder (MDD) and patterns of axonal injury.

methodsTwelve moderate-severe TBI patients and 26 controls were imaged using [

resultsLower [

conclusions[

Indexed as

AdultBrainBrain Injuries, TraumaticDiffusion Tensor ImagingFemaleHumansMajor Depressive DisorderMaleMiddle AgedPositron-Emission TomographyProtein BindingReceptors, Dopamine D2Receptors, Dopamine D3Young AdultDRD2 protein, humanDRD3 protein, humanReceptors, Dopamine D2Receptors, Dopamine D3DepressionDopaminePETTraumatic brain injury

Identifiers

PMID31352218
PMCPMC6664227
OpenAlexW2963856867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.