Evidence map›Paper›PMID 31352029›Full record

Trial reportBiological psychology2019

Brain structure changes induced by attention bias modification training.

Rany Abend, Ariel Rosenfelder, Dana Shamai, Daniel S Pine, Ido Tavor, Yaniv Assaf, Yair Bar-Haim

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Biological psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rany AbendSection on Development and Affective Neuroscience, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA. Electronic address: rany.abend@nih.gov.
Ariel RosenfelderSchool of Psychological Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
Dana ShamaiSchool of Psychological Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel; Sagol School of Neuroscience, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
Daniel S PineSection on Development and Affective Neuroscience, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Ido TavorSagol School of Neuroscience, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel; Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
Yaniv AssafDepartment of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel; Sagol School of Neuroscience, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
Yair Bar-HaimSchool of Psychological Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel; Sagol School of Neuroscience, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIA MH002781
6 · The paper itself

Abstract

Attention bias modification (ABM) therapy aims to reduce anxiety by changing threat-related attention patterns using computerized training tasks. We examined changes in brain microstructure following ABM training. Thirty-two participants were randomly assigned to one of two training conditions: active ABM training shifting attention away from threat or attention control training involving no attention modification. Participants completed six lab visits, including five training sessions and three diffusion tensor imaging scans: immediately before and after the first training session, and at the end of the training series. Indices of local and global changes in microstructure and connectivity were measured. Significant longitudinal differences in fractional anisotropy (FA) between the active and control training regimens occurred in inferior temporal cortex. Changes in FA occurred across groups within ventromedial prefrontal cortex and middle occipital gyrus. These results indicate specific effects of active ABM on brain structure. Such changes could relate to clinical effects of ABM.

Indexed as

Attentional BiasBehavior TherapyPsychotherapyAdultAnisotropyAnxiety DisordersBrainDiffusion Tensor ImagingFemaleHumansMaleOccipital LobePrefrontal CortexPsychiatric Status Rating ScalesReaction TimeTemporal LobeAnxietyAttention biasConnectivityDot probeDTIStructureTemporal cortex

Identifiers

PMID31352029
PMCPMC6718329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.