Evidence map›Paper›PMID 31351853›Full record

ArticleInternational journal of hygiene and environmental health2019

Self-reported residential pesticide use and survival after breast cancer.

Nicole M Niehoff, Marilie D Gammon, Humberto Parada, Steven D Stellman, Alfred I Neugut, Susan L Teitelbaum

Abstract read
In one paragraph

Article in International journal of hygiene and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicole M NiehoffDepartment of Epidemiology, University of North Carolina, 135 Dauer Drive, Chapel Hill, NC, 27599-7435, USA. Electronic address: nicole.niehoff@nih.gov.
Marilie D GammonDepartment of Epidemiology, University of North Carolina, 135 Dauer Drive, Chapel Hill, NC, 27599-7435, USA.
Humberto ParadaDivision of Epidemiology & Biostatistics, School of Public Health, San Diego State University, 5500 Campanile Drive, Hardy Tower Room 168, San Diego, CA, 92182, USA.
Steven D StellmanDepartment of Epidemiology, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Alfred I NeugutDepartment of Epidemiology, Columbia University, 722 West 168th Street, New York, NY, 10032, USA; Department of Medicine, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
Susan L TeitelbaumDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1057, New York, NY, 10029, USA.

Funding

Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
BREAST CANCER AND THE ENVIRONMENT ON LONG ISLANDU01CA066572 · NCI · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI GAMMON, MARILIE D · 1995 to 2004
$1.7M
NCI NIH HHS T32 CA057726NCI NIH HHS U01 CA066572NIEHS NIH HHS T32 ES007018
6 · The paper itself

Abstract

introductionPrevious investigations found elevated mortality after breast cancer in association with biomarkers of persistent organochlorine pesticides in non-occupationally exposed women. We hypothesized that lifetime residential pesticide use, which includes persistent and non-persistent pesticides, would also be associated with increased mortality after breast cancer.

methodsA population-based cohort of 1505 women with invasive or in situ breast cancer was interviewed in 1996-1997, shortly after diagnosis, about pre-diagnostic lifetime residential pesticide use. Participants were followed for mortality through 2014 (595 deaths from any cause and 236 from breast cancer, after 17.6 years of follow-up). Pesticides were examined as 15 individual categories; a group of seven used for lawn and garden purposes; a group of eight used for nuisance-pest purposes; and all combined. Cox regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause and breast cancer-specific mortality. Modification by estrogen receptor (ER) status, body mass index, and long-term residence was examined.

resultsEver use (HR = 0.77, 95%CI = 0.63-0.95) and higher lifetime applications (4th quartile: HR = 0.62, 95%CI = 0.47-0.81, p

conclusionsContrary to our hypothesis, lifetime residential use of lawn and garden pesticides, but not all combined or nuisance-pest pesticides, was inversely associated with all-cause mortality after breast cancer.

Indexed as

Environmental ExposureGardeningPesticidesAgedBreast NeoplasmsFemaleHumansMiddle AgedNew YorkSelf ReportPesticidesBreast cancerMortalityPesticide useResidential

Identifiers

PMID31351853
PMCPMC6732244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.